{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:29:45Z","timestamp":1777922985702,"version":"3.51.4"},"reference-count":72,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:p>\n                    This study investigated the occurrence of virulence and antimicrobial resistance properties in\n                    <jats:italic toggle=\"yes\">Vibrio<\/jats:italic>\n                    spp. isolated from hard-shelled mussel (\n                    <jats:italic toggle=\"yes\">Mytilus coruscus<\/jats:italic>\n                    ) marketed in Korea. A total of 32\n                    <jats:italic toggle=\"yes\">Vibrio<\/jats:italic>\n                    spp. isolates including\n                    <jats:italic toggle=\"yes\">Vibrio diabolicus<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200916),\n                    <jats:italic toggle=\"yes\">Vibrio alginolyticus<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200913),\n                    <jats:italic toggle=\"yes\">Vibrio parahaemolyticus<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20092), and\n                    <jats:italic toggle=\"yes\">Vibrio harveyi<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091) were identified by\n                    <jats:italic toggle=\"yes\">gyrB<\/jats:italic>\n                    gene sequencing. Every isolate grouped with their respective reference sequence excluding\n                    <jats:italic toggle=\"yes\">V. diabolicus<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">V. alginolyticus<\/jats:italic>\n                    that were intermixed in a neighbor-joining phylogenetic tree. Every\n                    <jats:italic toggle=\"yes\">Vibrio<\/jats:italic>\n                    spp. showed DNase and gelatinase activities. Phospholipase, slime, caseinase, lipase, \u03b2-hemolysis, and \u03b1-hemolysis were positive in 31 (96.8%), 31 (96.8%), 29 (93.5%), 28 (87.5%), 17 (53.1%), and 9 (28.1%) isolates, respectively. The PCR amplification of virulence genes displayed that\n                    <jats:italic toggle=\"yes\">V. alginolyticus<\/jats:italic>\n                    -specific (\n                    <jats:italic toggle=\"yes\">toxR, tlh, VAC<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">VPI<\/jats:italic>\n                    ) genes were detected in 23 (71.9%), 18 (56.3%), 21 (65.6%), and 26 (81.3%) isolates, respectively.\n                    <jats:italic toggle=\"yes\">V. parahaemolyticus<\/jats:italic>\n                    -specific (\n                    <jats:italic toggle=\"yes\">toxR<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">tlh<\/jats:italic>\n                    ) genes were harbored by 2 (6.3%) and 2 (6.3%) isolates, respectively. The other virulence genes including\n                    <jats:italic toggle=\"yes\">ctxAB<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">hupO<\/jats:italic>\n                    genes were observed in 23 (71.9%) and 16 (50.0%) isolates, respectively. The antimicrobial resistance was prevalent for amoxicillin (100.0%), ampicillin (100.0%), and streptomycin (37.5%) in disk diffusion test. Multiple antimicrobial resistance index ranged from 0.09 to 0.22. The extended-spectrum \u03b2-lactamase (ESBL) genes,\n                    <jats:italic toggle=\"yes\">blaCTX, blaTEM, blaSHV<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">blaOXA<\/jats:italic>\n                    were detected in 28 (87.5%), 13 (40.6%), 7 (21.8%), and 1 (3.1%) isolates, respectively. Non-ESBLs such as streptomycin resistance (\n                    <jats:italic toggle=\"yes\">strA.B<\/jats:italic>\n                    ), kanamycin resistance (\n                    <jats:italic toggle=\"yes\">aphA-IAB<\/jats:italic>\n                    ), and tetracycline resistance (\n                    <jats:italic toggle=\"yes\">tetE<\/jats:italic>\n                    ) genes were found in 5 (15.6%), 3 (9.4%), and 1 (3.1%) isolates. Class 1 integron-related Integrase 1 (\n                    <jats:italic toggle=\"yes\">intI1<\/jats:italic>\n                    ) gene was found in 8 (25.0%) isolates. Our results reveal that the consumption of raw mussels may cause a potential public health risks owing to the virulent and antimicrobial-resistant\n                    <jats:italic toggle=\"yes\">Vibrio<\/jats:italic>\n                    spp.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0131","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T14:05:52Z","timestamp":1570629952000},"page":"391-401","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Occurrence of Virulence and Extended-Spectrum \u03b2-Lactamase Determinants in\n                    <i>Vibrio<\/i>\n                    spp. Isolated from Marketed Hard-Shelled Mussel (\n                    <i>Mytilus coruscus<\/i>\n                    )"],"prefix":"10.1177","volume":"26","author":[{"given":"Sabrina","family":"Hossain","sequence":"first","affiliation":[{"name":"Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masimbule Vidanalage Kasun Sameera","family":"Wickramanayake","sequence":"additional","affiliation":[{"name":"Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pasan Sepala","family":"Dahanayake","sequence":"additional","affiliation":[{"name":"Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang-Joon","family":"Heo","sequence":"additional","affiliation":[{"name":"Veterinary Medical Center and College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,4,10]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"FAO. 2010. 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