{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T05:56:40Z","timestamp":1779083800647,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:p>\n                    IncF ColV plasmids are important plasmid incompatibility group that are currently restricted to the Enterobacteriaceae. These plasmids carry an important repertoire of virulence-associated genes (VAGs) that contribute to the ability of avian pathogenic\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    to cause disease in poultry. VAGs found on ColV plasmids have also been linked to urosepsis and meningitis in humans but the mechanisms that elicit these disease conditions are not well understood. Recently we described the sequence of a ColV plasmid pSDJ2009-52F that carried the typical repertoire of VAGs and a complex resistance gene locus flanked by IS\n                    <jats:italic toggle=\"yes\">26<\/jats:italic>\n                    , an insertion element that plays an important role in mobilizing antibiotic resistance genes on plasmids and genomic islands. We recovered complete ColV-like plasmid sequences from public databases that shared &gt;80% sequence identity with pSDJ2009-52F in geographically diverse regions of the world over a 20-year timeframe. Previously we noted that pSDJ2009-52F carries a unique genetic signature in the class 1 integron within the complex resistance locus that was presumably created by the action of IS\n                    <jats:italic toggle=\"yes\">26<\/jats:italic>\n                    . Here we show that most ColV-like plasmids that are closely related to pSDJ2009-52F also carry the same signature. Our studies provide insight into how these signature-bearing plasmids and the mobile genetic elements they carry traffic between\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    sequence types over large geographic distances.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0277","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T14:49:56Z","timestamp":1581086996000},"page":"787-793","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Molecular Analysis of an IncF ColV-Like Plasmid Lineage That Carries a Complex Resistance Locus with a Trackable Genetic Signature"],"prefix":"10.1177","volume":"26","author":[{"given":"Jessica","family":"McKinnon","sequence":"first","affiliation":[{"name":"ithree Institute, University of Technology Sydney, Sydney, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piklu","family":"Roy Chowdhury","sequence":"additional","affiliation":[{"name":"ithree Institute, University of Technology Sydney, Sydney, Australia."},{"name":"Australian Centre for Genomic Epidemiological Microbiology, University of Technology Sydney, NSW, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven P.","family":"Djordjevic","sequence":"additional","affiliation":[{"name":"ithree Institute, University of Technology Sydney, Sydney, Australia."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,7]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuw005"},{"key":"e_1_3_5_3_2","first-page":"e02068","article-title":"High genetic plasticity in multidrug-resistant sequence type 3-IncHI2 plasmids revealed by sequence comparison and phylogenetic analysis","volume":"62","author":"Fang L.X.","year":"2018","unstructured":"Fang L.X., , Li X.P, , Deng G.H, , Li S.M, , Yang R.S, , Wu Z.W, , Liao X.P, , Sun J., , and Liu Y.H.. 2018. High genetic plasticity in multidrug-resistant sequence type 3-IncHI2 plasmids revealed by sequence comparison and phylogenetic analysis. Antimicrob. Agents Chemother. 62:pii: e02068-17.","journal-title":"Antimicrob. Agents Chemother"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-144972"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078862"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2013.10.004"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.4161\/mge.1.1.16432"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015524"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2018.06.017"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-18273-2"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2016.0246"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.188.2.745-758.2006"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plasmid.2016.02.002"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.28.4.742-746.1990"},{"key":"e_1_3_5_15_2","first-page":"2272","article-title":"that causes neonatal meningitis is closely related to avian pathogenic E","volume":"77","author":"Peigne C.","unstructured":"Peigne C., , Bidet P., , Mahjoub-Messai F., , Plainvert C., , Barbe V., , Medigue C., , Frapy E., , Nassif X., , Denamur E., , Bingen E., , and Bonacorsi S.. 2009. The plasmid of Escherichia coli strain S88 (O45:K1:H7) that causes neonatal meningitis is closely related to avian pathogenic E. coli plasmids and is associated with high-level bacteremia in a neonatal rat meningitis model. Infect. Immun. 77:2272\u20132284.","journal-title":"coli plasmids and is associated with high-level bacteremia in a neonatal rat meningitis model. Infect. Immun"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01153-13"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112048"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2010.0042"},{"key":"e_1_3_5_19_2","first-page":"e01801","volume":"5","author":"Harmer C.J.","year":"2014","unstructured":"Harmer C.J., , Moran R.A, , and Hall R.M.. 2014. Movement of IS26-associated antibiotic resistance genes occurs via a translocatable unit that includes a single IS26 and preferentially inserts adjacent to another IS26. mBio, 5:e01801-14.","journal-title":"Movement of IS26-associated antibiotic resistance genes occurs via a translocatable unit that includes a single IS26 and preferentially inserts adjacent to another IS26. mBio"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2010.0033"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012754"},{"key":"e_1_3_5_22_2","first-page":"e000143","article-title":"Porcine commensal Escherichia coli: a reservoir for class 1 integrons associated with IS26","volume":"3","author":"Reid C.J.","year":"2017","unstructured":"Reid C.J., , Wyrsch E.R, , Roy Chowdhury P., , Zingali T., , Liu M., , Darling A.E, , Chapman T.A, , and Djordjevic S.P.. 2017. Porcine commensal Escherichia coli: a reservoir for class 1 integrons associated with IS26. Microb. Genom. 3:e000143.","journal-title":"Microb. Genom"},{"key":"e_1_3_5_23_2","doi-asserted-by":"crossref","first-page":"e0115781","DOI":"10.1371\/journal.pone.0115781","article-title":"A role for Tn6029 in the evolution of the complex antibiotic resistance gene loci in genomic island 3 in enteroaggregative hemorrhagic Escherichia coli O104:H4","volume":"10","author":"Roy Chowdhury P.","year":"2015","unstructured":"Roy Chowdhury P., , Charles I.G, , and Djordjevic S.P.. 2015. A role for Tn6029 in the evolution of the complex antibiotic resistance gene loci in genomic island 3 in enteroaggregative hemorrhagic Escherichia coli O104:H4. PLoS One, 10:e0115781.","journal-title":"PLoS One"},{"key":"e_1_3_5_24_2","volume-title":"Escherichia coli","author":"Roy Chowdhury P.","unstructured":"Roy Chowdhury P., , McKinnon J., , Liu M., , and Djordjevic S.P. 2019. Multidrug resistant uropathogenic Escherichia coli. ST405 with a novel, composite IS26 transposon in a unique chromosomal location. Front. Microbiol. 9: , 3212."},{"key":"e_1_3_5_25_2","volume-title":"E. coli","author":"Cummins M.L.","unstructured":"Cummins M.L., , Reid C., , Roy Chowdhury P., , Bushnell R.N, , Esbert N., , Tivendale K.A, , Noormohammadi A.H, , Islam S., , Marenda M.S, , Browning G.F, , Markham P.F, , and Djordjevic S.P. 2019. Whole genome sequence analysis of Australian avian pathogenic E. coli. that carry the class 1 integrase gene. Microb. Genom. 5. DOI: 10.1099\/mgen.0.00, 0250."},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2012.10.015"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2012.05.029"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02616-13"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2018.10.024"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv306"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0524-x"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003537"},{"key":"e_1_3_5_33_2","first-page":"e000094","article-title":"Genome-scale rates of evolutionary change in bacteria","volume":"2","author":"Duchene S.","year":"2016","unstructured":"Duchene S., , Holt K.E, , Weill F.X, , Le Hello S., , Hawkey J., , Edwards D.J, , Fourment M., , and Holmes E.C.. 2016. Genome-scale rates of evolutionary change in bacteria. Microb. Genom. 2:e000094.","journal-title":"Microb. Genom"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-402"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv195"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx488"},{"key":"e_1_3_5_37_2","article-title":"Escherichia coli ST131: a multidrug-resistant clone primed for global domination","author":"Pitout J.D.","year":"2017","unstructured":"Pitout J.D., , and DeVinney R.. 2017. Escherichia coli ST131: a multidrug-resistant clone primed for global domination. F1000Res 6:pii: F1000 Faculty Rev-195.","journal-title":"F1000Res 6:pii: F1000 Faculty Rev-195"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.226"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.63.3.507-522.1999"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12646"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01025-12"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1637\/11237-071715-Reg.1"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.08.007"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2014.06.009"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.1637\/10218-042812-ResNote.1"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03497.x"},{"key":"e_1_3_5_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00470-18"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0105016"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.plasmid.2016.11.001"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2017.01.007"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2019.0277","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2019.0277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2019.0277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:36:22Z","timestamp":1777667782000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/mdr.2019.0277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,1]]},"references-count":49,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7,1]]}},"alternative-id":["10.1089\/mdr.2019.0277"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2019.0277","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,1]]}}}