{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:30:17Z","timestamp":1777923017327,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T00:00:00Z","timestamp":1596153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>\n                    The aim of this study was to detect and characterize isolates of methicillin-\/oxacillin-resistant\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    (MRSA) carrying gene\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    (MRSA\/\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    ) and occurring in the Czech Republic within the period from 2002 to 2017. Altogether, 18 from 3,472 isolates of MRSA were\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    positive (0.52%). The first detection of MRSA\/\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    in the Czech Republic is dated to 2004. MRSA\/\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    isolates were susceptible to almost all tested antibiotics with few exceptions. Resistances to erythromycin (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20092), clindamycin (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091), trimethoprim-sulfamethoxazole (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091), and rifampicin (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091) were found in the collection. Multilocus sequence typing and\n                    <jats:italic toggle=\"yes\">spa<\/jats:italic>\n                    typing revealed a genetic heterogeneity of MRSA\/\n                    <jats:italic toggle=\"yes\">mecC<\/jats:italic>\n                    strains: three CCs (130, 425, and 2361), five STs (1245, 130, 2361, 425, and a new ST5480), and eight\n                    <jats:italic toggle=\"yes\">spa<\/jats:italic>\n                    types (t843, t978, t1048, t1535, t1736, t6104, t8842, and t17153), which were detected in the study, with the highest prevalence of CC130\/t843 lineage (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20098, 44%). Except for two strains, none from 18 examined isolates harbored genes encoding any of\n                    <jats:italic toggle=\"yes\">S. aureus<\/jats:italic>\n                    toxins: enterotoxins a\u2013u, exfoliative toxins A, B, and D, toxic shock syndrome toxin-1, and the Panton-Valentine leukocidin.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0319","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T14:40:32Z","timestamp":1582555232000},"page":"918-923","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Phenotype and Genotype Characteristics of\n                    <i>Staphylococcus aureus<\/i>\n                    Resistant to Methicillin\/Oxacillin Carrying Gene\n                    <i>mecC<\/i>\n                    in the Czech Republic from 2002 to 2017"],"prefix":"10.1177","volume":"26","author":[{"given":"Lucia","family":"Mali\u0161ov\u00e1","sequence":"first","affiliation":[{"name":"National Reference Laboratory for Antibiotics, Centre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladislav","family":"Jakub\u016f","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Antibiotics, Centre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic."},{"name":"Department of Clinical Microbiology, Faculty of Medicine and University Hospital, Charles University, Hradec Kralove, Czech Republic."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Mus\u00edlek","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Meningococcal Infections, Centre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Kekl\u00e1kov\u00e1","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Staphylococci, Centre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"\u017demli\u010dkov\u00e1","sequence":"additional","affiliation":[{"name":"National Reference Laboratory for Antibiotics, Centre for Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic."},{"name":"Department of Clinical Microbiology, Faculty of Medicine and University Hospital, Charles University, Hradec Kralove, Czech Republic."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,7,31]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"crossref","first-page":"E14","DOI":"10.3390\/tropicalmed4010014","article-title":"Nosocomial pathogens: an in-depth analysis of the vectorial potential of cockroaches","volume":"4","author":"Donkor E.S","year":"2019","unstructured":"Donkor E.S. 2019. Nosocomial pathogens: an in-depth analysis of the vectorial potential of cockroaches. Trop Med Infect Dis. 4: E14.","journal-title":"Trop Med Infect Dis"},{"key":"e_1_3_5_3_2","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1136\/bmj.1.5219.124-a","article-title":"Celbenin-resistant staphylococci","volume":"1","author":"Jevons, M.P","year":"1961","unstructured":"Jevons, M.P. 1961. Celbenin-resistant staphylococci. BMJ. 1:124\u2013125.","journal-title":"BMJ"},{"key":"e_1_3_5_4_2","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1093\/femsre\/fux007","article-title":"Antibiotic resistance in Staphylococcus aureus","volume":"41","author":"Foster, T.J","year":"2017","unstructured":"Foster, T.J. 2017. Antibiotic resistance in Staphylococcus aureus. Current status and future prospects. FEMS Microbiol Rev. 41:430\u2013449.","journal-title":"Current status and future prospects. 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