{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:59:47Z","timestamp":1790405987398,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      Clinical strains of\n                      <jats:italic toggle=\"yes\">Klebsiella quasipneumoniae<\/jats:italic>\n                      subsp.\n                      <jats:italic toggle=\"yes\">similipneumoniae<\/jats:italic>\n                      have been reported worldwide. Multidrug-resistant (MDR) hypermucoviscous (hm)\/hypervirulent (hv) lineages have become a global problem for public health worldwide. Therefore, this study aimed to characterize by whole-genome sequencing a MDR-hm\/hv\n                      <jats:italic toggle=\"yes\">K. quasipneumoniae<\/jats:italic>\n                      subsp.\n                      <jats:italic toggle=\"yes\">similipneumoniae<\/jats:italic>\n                      SWT10 strain belonging to the new sequence type ST4417 isolated from a sewage treatment plant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The SWT10 strain was recovered from a sewage treatment plant in Brazil and presented the hm and MDR phenotypes. Resistome analysis showed antimicrobial resistance genes associated with resistance to fluoroquinolones, \u03b2-lactams, tetracyclines, trimethoprim, aminoglycosides, sulfonamides, macrolides, and fosfomycin as well as several heavy metal resistance genes. Virulome analysis showed virulence factors related to hv lineages. Multilocus sequence typing analysis revealed the new ST4417, which was grouped in CC1584 by the minimum-spanning tree. Besides, five plasmid incompatibility groups, two prophage-related sequences, and 66 genomic islands were detected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      This study reports for the first time the genome sequence of a MDR-hm\/hv\n                      <jats:italic toggle=\"yes\">K. quasipneumoniae<\/jats:italic>\n                      subsp.\n                      <jats:italic toggle=\"yes\">similipneumoniae<\/jats:italic>\n                      recovered from the environment, which contributes to a better understanding about these lineages as well as for surveillance studies worldwide.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/mdr.2019.0417","type":"journal-article","created":{"date-parts":[[2020,1,17]],"date-time":"2020-01-17T15:10:11Z","timestamp":1579273811000},"page":"1321-1325","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Genomic Characterization of a Multidrug-Resistant and Hypermucoviscous\/Hypervirulent\n                    <i>Klebsiella quasipneumoniae<\/i>\n                    subsp.\n                    <i>similipneumoniae<\/i>\n                    ST4417 Isolated from a Sewage Treatment Plant"],"prefix":"10.1177","volume":"26","author":[{"given":"Jo\u00e3o Pedro Rueda","family":"Furlan","sequence":"first","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inara Fernanda Lage","family":"Gallo","sequence":"additional","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana Amabile","family":"de Campos","sequence":"additional","affiliation":[{"name":"Departamento de Biologia Celular, Instituto de Ci\u00eancias Biol\u00f3gicas, Universidade de Bras\u00edlia, Bras\u00edlia, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana Guedes","family":"Stehling","sequence":"additional","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_3_5_2_2","first-page":"and","article-title":"Description of Klebsiella quasipneumoniae sp","author":"Brisse S.","year":"2014","unstructured":"Brisse S., , Passet V., , and Grimont P.A.. 2014. 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Microbiol. 64:3146\u20133152.","journal-title":"nov., isolated from human infections, with two subspecies, Klebsiella quasipneumoniae subsp. quasipneumoniae subsp. nov. and Klebsiella quasipneumoniae subsp. similipneumoniae subsp"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-018-3365-9"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.4161\/viru.22718"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2011.06.007"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw569"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks261"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.06094-11"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02412-14"},{"key":"e_1_3_5_11_2","first-page":"e00438","volume":"4","author":"Elliott A.G.","year":"2016","unstructured":"Elliott A.G., , Ganesamoorthy D., , Coin L., , Cooper M.A, , and Cao M.D.. 2016. 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