{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:30:22Z","timestamp":1777923022496,"version":"3.51.4"},"reference-count":70,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    is the leading cause of foodborne illnesses worldwide. The widespread use of antimicrobials as prophylactic, therapeutic, and growth promoters in both livestock and human medicine has resulted in selective pressure regarding antimicrobial-resistant (AMR) bacteria. This systematic review summarizes phenotypic antimicrobial resistance profiles in\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates from human and swine sources between 1990 and 2018 in Brazil. The 20 studies that matched the eligibility criteria\u2014isolates from pigs and humans from Brazil, between 1990 and 2016, containing information on the number of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolates, and applying the disk diffusion susceptibility method\u2014were included. During the assessed period,\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    strains isolated from swine sources displayed the highest resistance rates for tetracycline (20.3%) and sulfonamides (17.4%). In contrast, human isolates displayed the highest resistance rates against ampicillin (19.8%) and tetracycline (17%).\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Typhimurium was the most frequent AMR isolate from both swine and human sources, corresponding to 67% of all isolates. From 2001 to 2005, tetracycline and ampicillin were the top antimicrobial resistance compounds, and the most frequently detected in swine and human sources, respectively. A total of 63 and 58 multiple drug resistance profiles were identified in swine and human isolates, respectively. Antimicrobial resistance has decreased throughout the 1990\u20132016 period, except for gentamicin and nalidixic acid in swine and human isolates, respectively. The results indicate that\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    isolated from human and swine display resistance against clinically important antimicrobials, indicating that swine are possibly one of the main vectors for spreading human salmonellosis in Brazil.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2019.0475","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T16:46:41Z","timestamp":1589561201000},"page":"1260-1270","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Antimicrobial Resistance in Nontyphoidal\n                    <i>Salmonella<\/i>\n                    Isolates from Human and Swine Sources in Brazil: A Systematic Review of the Past Three Decades"],"prefix":"10.1177","volume":"26","author":[{"given":"Grazielle Lima","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Institute of Chemistry, Federal University of Rio de Janeiro, Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."},{"name":"Center for Food Analysis, Technological Development Support Laboratory (LADETEC), Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Panzenhagen","sequence":"additional","affiliation":[{"name":"Institute of Chemistry, Federal University of Rio de Janeiro, Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."},{"name":"Center for Food Analysis, Technological Development Support Laboratory (LADETEC), Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafaela Gomes","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Institute of Chemistry, Federal University of Rio de Janeiro, Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."},{"name":"Center for Food Analysis, Technological Development Support Laboratory (LADETEC), Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vania Margaret Flosi","family":"Paschoalin","sequence":"additional","affiliation":[{"name":"Institute of Chemistry, Federal University of Rio de Janeiro, Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Adam","family":"Conte-Junior","sequence":"additional","affiliation":[{"name":"Institute of Chemistry, Federal University of Rio de Janeiro, Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."},{"name":"Center for Food Analysis, Technological Development Support Laboratory (LADETEC), Cidade Universit\u00e1ria, Rio de Janeiro, Brazil."},{"name":"Faculty of Veterinary Medicine, Analytical and Molecular Laboratory Center, Fluminense Federal University, Niter\u00f3i, Brazil."},{"name":"National Institute of Health Quality Control, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,28]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/s41540-017-0034-z","article-title":"SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation","volume":"3","author":"M\u00e9tris A.","year":"2017","unstructured":"M\u00e9tris A., , Sudhakar P., , Fazekas D., , Demeter A., , Ari E., , Olbei M., , Branchu P., , Kingsley R.A, , Baranyi J., , and Korcsm\u00e1ros T.. 2017. SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation. Npj. Syst. Biol. Appl. 3:31.","journal-title":"Npj. Syst. Biol. Appl"},{"key":"e_1_3_4_3_2","first-page":"4634","article-title":"The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2015","volume":"14","author":"for D.P.","year":"2016","unstructured":"European Food Safety Authority, E.C. for D.P. and C. 2016. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2015. 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