{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:30:38Z","timestamp":1777923038990,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>\n                      This study aimed to investigate recent national surveillance trends in\n                      <jats:italic toggle=\"yes\">Staphylococcus epidermidis<\/jats:italic>\n                      antibiotic resistance in Scotland and to draw conclusions on the potential clinical and public health impact of multidrug-resistant isolates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Resistance in\n                      <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                      isolates to individual agents was broadly stable over the past 5 years. Isolates from sterile sites, and therefore those most likely to be associated with clinical infection, were found to be more resistant to the majority of reported agents, than isolates from nonsterile sites. Increased resistance to a number of important antibiotics was observed in rifampicin-, vancomycin-, and daptomycin-resistant isolates, suggesting limited treatment options for infections caused by these isolates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Although\n                      <jats:italic toggle=\"yes\">S. epidermidis<\/jats:italic>\n                      resistance to individual agents has been broadly stable over the past 5 years nationally, of particular concern is the association of multidrug resistance in rifampicin-resistant isolates, which has been reported elsewhere. This has the potential to result in treatment failures in significant device-related infections.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/mdr.2019.0502","type":"journal-article","created":{"date-parts":[[2020,8,16]],"date-time":"2020-08-16T15:59:22Z","timestamp":1597593562000},"page":"485-491","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiological Analysis of Antimicrobial Resistance in\n                    <i>Staphylococcus epidermidis<\/i>\n                    in Scotland, 2014\u20132018"],"prefix":"10.1177","volume":"27","author":[{"given":"Adriana","family":"Zalewska","sequence":"first","affiliation":[{"name":"Public Health Scotland, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Wilson","sequence":"additional","affiliation":[{"name":"Public Health Scotland, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Public Health Scotland, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Lockhart","sequence":"additional","affiliation":[{"name":"Public Health Scotland, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mairi","family":"MacLeod","sequence":"additional","affiliation":[{"name":"NHS Greater Glasgow and Clyde, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Malcolm","sequence":"additional","affiliation":[{"name":"Public Health Scotland, Glasgow, United Kingdom."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1128\/JCM.44.5.1922-1923.2006","article-title":"High prevalence of teicoplanin resistance among Staphylococcus epidermidis strains in a 5-year retrospective study","volume":"44","author":"Trueba F.","year":"2006","unstructured":"Trueba F., , Garrabe E., , Hadef R., , Fabre R., , Cavallo J.D, , Tsvetkova K., , and Chesneau O.. 2006. 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