{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T21:34:55Z","timestamp":1788384895308,"version":"build-2803163510"},"reference-count":49,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2020,11,1]]},"abstract":"<jats:p>\n                    Diarrheagenic\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    cause diarrheal diseases, which are a public health concern and affect mainly developing countries. Multidrug-resistant (MDR) pathogens have been spreading in different sources, including animals and the environment.\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains were obtained from a small-scale pig farm and 33 antimicrobials were tested. All strains were classified as MDR and harbored several antimicrobial resistance genes (ARGs) [\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CMY<\/jats:sub>\n                    ,\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>\n                      OXA-1-\n                      <jats:italic toggle=\"yes\">like<\/jats:italic>\n                    <\/jats:sub>\n                    ,\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>SHV<\/jats:sub>\n                    ,\n                    <jats:italic toggle=\"yes\">tet(A)<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">tet(B)<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">aad<\/jats:italic>\n                    A,\n                    <jats:italic toggle=\"yes\">aac(6\u2019)-Ib<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">aph(3\u2032)-Ia<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">sul1<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">sul2<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">sul3<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">floR<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">cml<\/jats:italic>\n                    A] and plasmids. Besides, mutations in quinolone resistance-determining region of GyrA (Ser83Leu and Asp87Asn) and ParC (Glu84Asp) were detected. Among the MDR\n                    <jats:italic toggle=\"yes\">E. coli,<\/jats:italic>\n                    nine strains (52%) presented diarrheagenic virulence genes, including genes related to Shiga toxin-producing\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    (STEC), enteroinvasive\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    (EIEC), and enteroaggregative\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    (EAEC). The pulsed-field gel electrophoresis results showed a high genetic diversity among the MDR\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    strains. Multilocus sequence typing (MLST) analyses revealed different sequence types phylogenetically related to each other, including ST10 and ST56. Subtyping of MLST by\n                    <jats:italic toggle=\"yes\">fimH<\/jats:italic>\n                    gene showed different\n                    <jats:italic toggle=\"yes\">fimH type<\/jats:italic>\n                    . This study shows a high genetic diversity among MDR ARG-producing\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    belonging to STEC, EIEC, and EAEC pathotypes obtained from a small-scale pig farm and contributes to the monitoring of antimicrobial-resistant pathogens worldwide, mainly in environmental samples, which are associated with One Health framework.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2020.0090","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T18:01:06Z","timestamp":1588874466000},"page":"1365-1371","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Genetic Diversity of Multidrug-Resistant CMY-Producing\n                    <i>Escherichia coli<\/i>\n                    from Feces and Soil in a Small-Scale Pig Farm"],"prefix":"10.1177","volume":"26","author":[{"given":"Jo\u00e3o Pedro Rueda","family":"Furlan","sequence":"first","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo (USP), Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcia Eliana","family":"da Silva Ferreira","sequence":"additional","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo (USP), Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana Guedes","family":"Stehling","sequence":"additional","affiliation":[{"name":"Departamento de An\u00e1lises Cl\u00ednicas, Toxicol\u00f3gicas e Bromatol\u00f3gicas, Faculdade de Ci\u00eancias Farmac\u00eauticas de Ribeir\u00e3o Preto, Universidade de S\u00e3o Paulo (USP), Ribeir\u00e3o Preto, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,10,28]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjm.2016.10.015"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31826df662"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12147"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1002-0160(18)60062-1"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/hs.2014.0088"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/20477724.2019.1693712"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-017-0225-x"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2018.00306"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.173.2.697-703.1991"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2011.03570.x"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp498"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.1.157"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-2508(99)80057-6"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.06191-11"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm204"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1006\/mcpr.2001.0363"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf164"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.3.1169-1172.2003"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn166"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.2.421-424.2000"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph120505177"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2005.03.018"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn470"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.33.3.701-705.1995"},{"key":"e_1_3_5_26_2","doi-asserted-by":"crossref","unstructured":"Paton A.W. and Paton J.C.. 1998. 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