{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T03:53:13Z","timestamp":1790394793752,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T00:00:00Z","timestamp":1622160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>\n                    The occurrence and characterization of carbapenemase-producing Enterobacteriaceae from companion animals in Guangzhou, China, are investigated. Six isolates (2.3%, 6\/257) were positive for\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>NDM-5<\/jats:sub>\n                    , that is, one\n                    <jats:italic toggle=\"yes\">Enterobacter cloacae<\/jats:italic>\n                    , one\n                    <jats:italic toggle=\"yes\">Citrobacter freundii<\/jats:italic>\n                    , and four\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    . Three\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    isolates obtained from the same animal hospital were ST410 and showed identical pulse field gel electrophoresis pattern, resistance profiles, and resistance genes.\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>NDM-5<\/jats:sub>\n                    was located on IncX3 (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20095) and IncK2 (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20091) plasmid, respectively. The presence of carbapenemase-producing Enterobacteriaceae among companion animals needs continued surveillance.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2020.0210","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T17:02:57Z","timestamp":1605891777000},"page":"809-815","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Emergence of\n                    <i>bla<\/i>\n                    <sub>NDM-5<\/sub>\n                    in Enterobacteriaceae Isolates from Companion Animals in Guangzhou, China"],"prefix":"10.1177","volume":"27","author":[{"given":"Jing","family":"Wang","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."},{"name":"Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of Agriculture of China, Yangzhou University, Yangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Bi","family":"Xia","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yi","family":"Huang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality, Ministry of Agriculture of China, Yangzhou University, Yangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu-Chao","family":"Lv","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Qing","family":"Lin","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Ying","family":"Yi","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Lan","family":"Lu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian\u2013Hua","family":"Liu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Ling","family":"Zeng","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, Key Laboratory of Zoonoses, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, China."},{"name":"Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,28]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2016.09.002"},{"key":"e_1_3_5_3_2","first-page":"20809","article-title":"New Delhi Metallo-beta-lactamase around the world: an eReview using Google Maps","author":"Berrazeg M.","year":"2014","unstructured":"Berrazeg M., , Diene S., , Medjahed L., , Parola P., , Drissi M., , Raoult D., , and Rolain J.. 2014. New Delhi Metallo-beta-lactamase around the world: an eReview using Google Maps. Euro. Surveill. 19. pii:20809.","journal-title":"Euro. Surveill. 19"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.24272\/j.issn.2095-8137.2017.024"},{"key":"e_1_3_5_5_2","first-page":"E40","article-title":"Resistance to carbapenems in non-typhoidal Salmonella enterica Serovars from humans, animals and food","author":"Ferm\u00e1ndez J.","year":"2018","unstructured":"Ferm\u00e1ndez J., , Guerra B., , and Rodicio M.R.. 2018. Resistance to carbapenems in non-typhoidal Salmonella enterica Serovars from humans, animals and food. Vet. Sci. 5. pii:E40.","journal-title":"Vet. Sci. 5"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2018.0237"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2019.0382"},{"key":"e_1_3_5_8_2","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/zph.12676","article-title":"Circulation of emerging NDM-5-producing Escherichia coli among humans and dogs in Egypt","volume":"67","author":"Ramadan H.","year":"2019","unstructured":"Ramadan H., , Gupta S.K, , Sharma P., , Ahmed M., , Hiott L.M, , Barrett J.B, , Woodley T.A, , Frye J.G, , and Jackson C.R.. 2019. Circulation of emerging NDM-5-producing Escherichia coli among humans and dogs in Egypt. Zoonoses Public Health. 67:324\u2013329.","journal-title":"Zoonoses Public Health"},{"key":"e_1_3_5_9_2","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1093\/jac\/dkz017","article-title":"Occurrence and characterization of Escherichia coli ST410 co-harbouring bla\n                  NDM-5, bla\n                  CMY-42 and bla\n                  TEM-90 in a dog from the UK","volume":"74","author":"Reynolds M.E.","year":"2019","unstructured":"Reynolds M.E., , Phan H.T.T, , George S., , Hubbard A.T.M, , Stoesser N., , Maciuca I.E, , Crook D.W, , and Timofte D.. 2019. Occurrence and characterization of Escherichia coli ST410 co-harbouring blaNDM-5, blaCMY-42 and blaTEM-90 in a dog from the UK. J. Antimicrob. Chemother. 74:1207\u20131211.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_5_10_2","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jgar.2017.10.021","article-title":"bla\n                  NDM-1-producing multidrug-resistant Escherichia coli isolated from a companion dog in China","volume":"13","author":"Cui L.","year":"2018","unstructured":"Cui L., , Lei L., , Lv Y., , Zhang R., , Liu X., , Li M., , Zhang F., , and Wang Y.. 2018. blaNDM-1-producing multidrug-resistant Escherichia coli isolated from a companion dog in China. J. Glob. Antimicrob. Resist. 13:24\u201327.","journal-title":"J. Glob. Antimicrob. Resist"},{"key":"e_1_3_5_11_2","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.3389\/fmicb.2019.02852","article-title":"Increasing prevalence of ESBL-producing multidrug resistance Escherichia coli from diseased pets in Beijing, China from 2012 to 2017","volume":"10","author":"Chen Y.","year":"2019","unstructured":"Chen Y., , Liu Z., , Zhang Y., , Zhang Z., , Lei L., , and Xia Z.. 2019. Increasing prevalence of ESBL-producing multidrug resistance Escherichia coli from diseased pets in Beijing, China from 2012 to 2017. Front. Microbiol. 10:2852.","journal-title":"Front. Microbiol"},{"key":"e_1_3_5_12_2","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.3389\/fmicb.2018.02989","article-title":"Clonal spread of Escherichia coli ST93 carrying mcr-1-harboring IncN1-IncHI2\/ST3 plasmid among companion animals, China","volume":"9","author":"Wang J.","year":"2018","unstructured":"Wang J., , Huang X.Y, , Xia Y.B, , Guo Z.W, , Ma Z.B, , Yi M.Y, , Lv L.C, , Lu P.L, , Yan J.C, , Huang J.W, , Zeng Z.L, , and Liu J.H. 2018. Clonal spread of Escherichia coli ST93 carrying mcr-1-harboring IncN1-IncHI2\/ST3 plasmid among companion animals, China. Front. Microbiol. 9:2988.","journal-title":"Front. Microbiol"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.12.002"},{"key":"e_1_3_5_14_2","first-page":"USA","article-title":"Performance Standards for Antimicrobial Susceptibility Testing","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2018","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 2018. Performance Standards for Antimicrobial Susceptibility Testing. CLSI Supplement M100, 28th ed. CLSI, Wayne,, PA, USA.","journal-title":"CLSI Supplement M100, 28th ed. CLSI, Wayne,"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.35.11.2977-2980.1997"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2006.05172.x"},{"key":"e_1_3_5_17_2","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1038\/s42003-019-0569-1","article-title":"Key evolutionary events in the emergence of a globally disseminated, carbapenem resistant clone in the Escherichia coli ST410 lineage","volume":"2","author":"Feng Y.","year":"2019","unstructured":"Feng Y., , Liu L., , Lin J., , Ma K., , Long H., , Wei L., , Xie Y., , McNally A., , and Zong Z.. 2019. Key evolutionary events in the emergence of a globally disseminated, carbapenem resistant clone in the Escherichia coli ST410 lineage. Commun. Biol. 2:322.","journal-title":"Commun. Biol"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm065"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(83)80284-8"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1995.1220"},{"key":"e_1_3_5_21_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.plasmid.2012.03.001","article-title":"Expansion of the IncX plasmid family for improved identification and typing of novel plasmids in drug-resistant Enterobacteriaceae","volume":"68","author":"Johnson T.J.","year":"2012","unstructured":"Johnson T.J., , Bielak E.M, , Fortini D., , Hansen L.H, , Hasman H., , Debroy C., , Nolan L.K, , and Carattoli A.. 2012. Expansion of the IncX plasmid family for improved identification and typing of novel plasmids in drug-resistant Enterobacteriaceae. Plasmid, 68:43\u201350.","journal-title":"Plasmid"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2005.03.018"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-9-75"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2017.00407"},{"key":"e_1_3_5_25_2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.plasmid.2015.04.009","article-title":"IncI shufflons: assembly issues in the next-generation sequencing era","volume":"80","author":"Brouwer M.S.","year":"2015","unstructured":"Brouwer M.S., , Tagg K.A, , Mevius D.J, , Iredell J.R, , Bossers A., , Smith H.E, , and Partridge S.R.. 2015. IncI shufflons: assembly issues in the next-generation sequencing era. Plasmid, 80:111\u2013117.","journal-title":"Plasmid"},{"key":"e_1_3_5_26_2","doi-asserted-by":"crossref","first-page":"2261","DOI":"10.1093\/jac\/dky176","article-title":"Emergence of XDR Escherichia coli carrying both bla\n                  NDM and mcr-1 genes in chickens at slaughter and the characterization of two novel bla\n                  NDM-bearing plasmids","volume":"73","author":"Lv L.","year":"2018","unstructured":"Lv L., , Zeng Z., , Song Q., , Cao Y., , Wang J., , Li W., , Wen Q., , Zhang Q., , Wan M., , Yang J., , and Liu J.H.. 2018. Emergence of XDR Escherichia coli carrying both blaNDM and mcr-1 genes in chickens at slaughter and the characterization of two novel blaNDM-bearing plasmids. J. Antimicrob. Chemother. 73:2261\u20132263.","journal-title":"J. Antimicrob. Chemother"},{"key":"e_1_3_5_27_2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S1473-3099(16)00057-8","article-title":"Carbepenem-resistant and colistin-resistant Escherichia coli co-producing NDM-9 and MCR-1","volume":"16","author":"Yao X.","year":"2016","unstructured":"Yao X., , Doi Y., , Zeng L., , Lv L., , and Liu J.H.. 2016. Carbepenem-resistant and colistin-resistant Escherichia coli co-producing NDM-9 and MCR-1. Lancet Infect. Dis. 16:288\u2013289.","journal-title":"Lancet Infect. Dis"},{"key":"e_1_3_5_28_2","first-page":"e01245","article-title":"Heterogeneous genetic location of mcr-1 in colistin-resistant Escherichia coli isolated from humans and retail chicken meat in Switzerland: emergence of mcr-1-carrying IncK2 plasmids","author":"Don\u00e0 V.","year":"2017","unstructured":"Don\u00e0 V., , Bernasconi O.J, , Pires J., , Collaud A., , Overesch G., , Ramette A., , Perreten V., , and Endimiani A.. 2017. Heterogeneous genetic location of mcr-1 in colistin-resistant Escherichia coli isolated from humans and retail chicken meat in Switzerland: emergence of mcr-1-carrying IncK2 plasmids. Antimicrob. Agents Chemother. 61. pii:e01245\u201317.","journal-title":"Antimicrob. Agents Chemother. 61"},{"key":"e_1_3_5_29_2","first-page":"e01954","article-title":"Plasmids of distinct IncK lineages show compatible phenotypes","author":"Rozwandowicz M.","year":"2017","unstructured":"Rozwandowicz M., , Brouwer M.S, , Zomer A.L, , Bossers A., , Harders F., , Mevius D.J, , Wagenaar J.A, , and Hordijk J.. 2017. Plasmids of distinct IncK lineages show compatible phenotypes. Antimicrob. Agents Chemother. 61. pii:e01954\u201316.","journal-title":"Antimicrob. Agents Chemother. 61"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1089\/fpd.2018.2531"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2020.0210","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2020.0210","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2020.0210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:38:03Z","timestamp":1777667883000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/mdr.2020.0210"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,28]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1089\/mdr.2020.0210"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2020.0210","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,28]]}}}