{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T11:03:08Z","timestamp":1785927788274,"version":"3.56.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:p>\n                    Concerns have been raised regarding co-selection for antibiotic resistance among bacteria exposed to antibiotics used as growth promoters for some livestock and poultry species. Tetracycline had been commonly used for this purpose worldwide, and its residue has been associated with selection of resistant bacteria in aquatic biofilms. This study aimed to determine the resistance profile, the existence of some beta-lactamases genes and the capacity to form biofilm of bacteria isolated from water samples previously exposed to tetracycline (20\u2009mg\/L). Thirty-seven tetracycline-resistant bacterial strains were identified as\n                    <jats:italic toggle=\"yes\">Serratia marcescens<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Morganella morganii<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Pseudomonas aeruginosa<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Citrobacter freundii<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Providencia alcalifaciens<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Enterococcus faecium<\/jats:italic>\n                    . The highest percentage of resistance was for ampicillin (75.75%) and amoxicillin\/clavulanic acid (66.66%) in the Gram-negative bacteria and an\n                    <jats:italic toggle=\"yes\">E. faecium<\/jats:italic>\n                    strain showed high resistance to vancomycin (minimum inhibitory concentration 250\u2009\u03bcg\/mL). Among the strains analyzed, 81.09% had multidrug resistance and eight Gram-negatives carried the\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>OXA-48<\/jats:sub>\n                    gene. All strains were able to form biofilm and 43.23% were strong biofilm formers. This study suggests that resistant bacteria can be selected under selection pressure of tetracycline, and that these bacteria could contribute to the maintenance and spread of antimicrobial resistance in this environment.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2021.0255","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T17:47:47Z","timestamp":1648144067000},"page":"654-659","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Analysis of Antibiotic Resistance and Biofilm-Forming Capacity in Tetracycline-Resistant Bacteria from a Coastal Lagoon"],"prefix":"10.1177","volume":"28","author":[{"given":"Aline Reis","family":"M\u00fcller","sequence":"first","affiliation":[{"name":"Department of Microbiology, Immunology and Parasitology, Institute of Basic Health Science, Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belize Rodrigues","family":"Leite","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Parasitology, Institute of Basic Health Science, Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gertrudes","family":"Cor\u00e7\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology and Parasitology, Institute of Basic Health Science, Universidade Federal do Rio Grande do Sul, Rio Grande do Sul, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,10]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2013.11.001"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2013.01.032"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-090110-102911"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.4.1123-1129.2006"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01009-09"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01312-09"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1701.100244"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.028308-0"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0213-005X(14)70168-5"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00454-09"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2019.03.006"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1078\/1438-4221-00196"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/08927010902833443"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-179"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1897\/04-182R.1"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2016.02.103"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.05.005"},{"key":"e_1_3_4_19_2","first-page":"2379","article-title":"Antibiotic resistance in surface waters from a coastal lagoon of Southern Brazil under the impact of anthropogenic activities","volume":"14","author":"Leite B.","year":"2019","unstructured":"Leite B., , de Chaves M.A, , Nunes A.A.T, , Jank L., , and Cor\u00e7\u00e3o G.. 2019. 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