{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:01:07Z","timestamp":1787169667982,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                    Recurrent urinary tract infections (UTIs) are a challenging clinical entity that can be frustrating for patient and physician alike. Repeated rounds of antibiotics can select for multidrug-resistant organisms, further complicating care. We describe the successful use of fecal microbiota transplantation (FMT) for the treatment of recurrent extended-spectrum \u03b2-lactamase (ESBL)-producing\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    UTIs in a patient with an ileal conduit and urostomy. In the 18 months after FMT, the patient had not experienced new infections with ESBL-producing organisms. The urine and stool microbiomes of the patient were tracked before and post-FMT using 16s RNA sequencing with measurement of \u03b1-diversity. Sequencing of the recipient microbiota did not mirror the donor stool taxa at either site, but an increase in the relative proportion of the genus\n                    <jats:italic toggle=\"yes\">Bacteroides<\/jats:italic>\n                    as compared with\n                    <jats:italic toggle=\"yes\">Prevotella<\/jats:italic>\n                    was noted in the stool post-transplant. FMTs may be a promising treatment option for recurrent multidrug-resistant infections.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2022.0031","type":"journal-article","created":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T13:19:03Z","timestamp":1672233543000},"page":"34-38","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["A Case of Successful Treatment of Recurrent Urinary Tract Infection by Extended-Spectrum \u03b2-Lactamase Producing\n                    <i>Klebsiella pneumoniae<\/i>\n                    Using Oral Lyophilized Fecal Microbiota Transplant"],"prefix":"10.1177","volume":"29","author":[{"given":"Naomi","family":"Bier","sequence":"first","affiliation":[{"name":"Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA."},{"name":"Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blake","family":"Hanson","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA."},{"name":"Center for Antimicrobial Resistance and Microbial Genomics, McGovern Medical School, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Dong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert L.","family":"DuPont","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases, University of Texas Health Science Center, School of Public Health, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar A.","family":"Arias","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Houston Methodist Hospital, Houston, Texas, USA."},{"name":"Center for Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas, USA."},{"name":"Molecular Genetics and Antimicrobial Resistance Unit, Universidad El Bosque, Bogota, Colombia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1518-2973","authenticated-orcid":false,"given":"William R.","family":"Miller","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Internal Medicine, Houston Methodist Hospital, Houston, Texas, USA."},{"name":"Center for Infectious Diseases Research, Houston Methodist Research Institute, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,17]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2018.05.005"},{"key":"e_1_3_3_3_2","first-page":"1","article-title":"The role of gut, vaginal, and urinary microbiome in urinary tract infections: from bench to bedside","volume":"11","author":"Mestrovic T.","year":"2020","unstructured":"Mestrovic T., , Matijasic M., , Peric M., , Cipcic Paljetak H., , Baresic A., , and Verbanac D.. 2020. 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