{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:27:16Z","timestamp":1790720836874,"version":"4.1.0"},"reference-count":54,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2022,7,1]]},"abstract":"<jats:p>\n                    An attributing factor to Enterobacterales producing extended-spectrum beta-lactamase (ESBL-E) community spread is human-to-human transmission. This systematic review and meta-analysis aimed to estimate the duration of ESBL-E carriage in the community and the rate of household transmission. Literature search was performed on PubMed, EMBASE, and Scopus. Dose-response meta-analysis was planned to model the proportion of ESBL-E carriers and household transmission over time. Twenty-six studies (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u20092,505 participants) were included. The median carriage duration was 2 months. Approximately 22% (95% confidence interval: 16\u201328) had persistent carriage after 12 months. Travelers had significantly shorter carriage (median 1\u20132 months) than discharged hospital patients (median 6 months) at all measured time points. There were insufficient data to robustly meta-analyze household transmission. Nonetheless, five longitudinal studies reported 18.4% to 35.2% of contacts acquired ESBL-E within 4 to 36 months from hospital discharge of index case. Transmission events from travelers to their contacts appeared lower. Travelers with travel-acquired ESBL-E had significantly faster decolonization rate than discharged patients, suggesting that travel-associated import of multidrug-resistant pathogen may have limited contribution to community transmission of ESBL-E. The substantial prevalence of persistent carriers warrant consideration for additional measures to mitigate exposure risk of ESBL-E from discharged patients in the community and from readmitting patients in the hospital.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2022.0035","type":"journal-article","created":{"date-parts":[[2022,6,21]],"date-time":"2022-06-21T09:19:04Z","timestamp":1655803144000},"page":"795-805","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":23,"title":["Carriage Duration and Household Transmission of Enterobacterales Producing Extended-Spectrum Beta-Lactamase in the Community: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5803-3831","authenticated-orcid":false,"given":"Weiping","family":"Ling","sequence":"first","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Maria","family":"Peri","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Furuya-Kanamori","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick N.A.","family":"Harris","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia."},{"name":"Central Microbiology, Pathology Queensland, Royal Brisbane &amp; Women's Hospital, Brisbane, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Paterson","sequence":"additional","affiliation":[{"name":"UQ Centre for Clinical Research, Faculty of Medicine, University of Queensland, Brisbane, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00023-13"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx146"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkaa399"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq415"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00135-18"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2542-5196(19)30130-5"},{"key":"e_1_3_6_8_2","first-page":"62","volume":"133","author":"Blakiston M.R.","year":"2020","unstructured":"Blakiston M.R., , and Freeman J.T.. 2020. Population-level exposures associated with MRSA and ESBL-E. coli infection across district health boards in Aotearoa New Zealand: an ecological study. N. Z. Med. J. 133:62\u201369.","journal-title":"Population-level exposures associated with MRSA and ESBL-E. coli infection across district health boards in Aotearoa New Zealand: an ecological study. N. Z. Med. J"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-020-00803-9"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taw101"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw283"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.106041"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.07.025"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlab068"},{"key":"e_1_3_6_15_2","first-page":"2008","article-title":"Meta-analysis of observational studies in epidemiology: a proposal for reporting","volume":"283","author":"Stroup D.F.","year":"2000","unstructured":"Stroup D.F., , Berlin J.A, , Morton S.C, et al. 2000. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group. JAMA, 283:2008\u20132012.","journal-title":"Meta-analysis of Observational Studies in Epidemiology (MOOSE) group. JAMA"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-016-0384-4"},{"key":"e_1_3_6_17_2","unstructured":"Tufanaru C. Z. Munn E. Aromataris J. Campbell and L. Hopp. Chapter 3: systematic reviews of effectiveness. In: E. Aromataris and Z. Munn (eds). Joanna Briggs Institute Reviewer's Manual. The Joanna Briggs Institute 2017."},{"key":"e_1_3_6_18_2","unstructured":"Wells G.A. B. Shea D. O'Connell J. Peterson V. Welch M. Losos and P. Tugwell. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Available at http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1097\/XEB.0000000000000132"},{"key":"e_1_3_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ020"},{"key":"e_1_3_6_21_2","first-page":"Boston","article-title":"REMR: stata module to implement robust error meta-regression method for dose\u2013response meta-analysis","volume":"458793","author":"Furuya-Kanamori L.","year":"2021","unstructured":"Furuya-Kanamori L., , Xu C., , and Doi S.A.. 2021. REMR: stata module to implement robust error meta-regression method for dose\u2013response meta-analysis. Statistical Software Components, S458793, Boston College Department of Economics.","journal-title":"Statistical Software Components"},{"key":"e_1_3_6_22_2","doi-asserted-by":"crossref","first-page":"e0205504","DOI":"10.1371\/journal.pone.0205504","article-title":"Duration of travel-associated faecal colonisation with ESBL-producing Enterobacteriaceae\u2014a one year follow-up study","volume":"13","author":"T\u00e4rnberg M.","year":"2018","unstructured":"\u00d6stholmBalkhed, \u00c5., T\u00e4rnberg M., , Nilsson M., , Nilsson L.E, , Hanberger H., , and H\u00e4llgren A.. 2018. Duration of travel-associated faecal colonisation with ESBL-producing Enterobacteriaceae\u2014a one year follow-up study. PLoS One, 13:e0205504.","journal-title":"PLoS One"},{"key":"e_1_3_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)30319-X"},{"key":"e_1_3_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2014.12.001"},{"key":"e_1_3_6_25_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1908.130257"},{"key":"e_1_3_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2018.10.012"},{"key":"e_1_3_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.03.002"},{"key":"e_1_3_6_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00220-10"},{"key":"e_1_3_6_29_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2011.653582"},{"key":"e_1_3_6_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa543"},{"key":"e_1_3_6_31_2","volume-title":"Escherichia coli","author":"Bevan E.R.","unstructured":"Bevan E.R., , McNally A., , Thomas C.M, , Piddock L.J.V, , and Hawkey P.M. 2018. Acquisition and loss of CTX-M-producing and non-producing Escherichia coli. in the fecal microbiome of travelers to South Asia. MBio 9: e02408\u2013e0, 2418."},{"key":"e_1_3_6_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2012.05.015"},{"key":"e_1_3_6_33_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208505"},{"key":"e_1_3_6_34_2","article-title":"Quantifying within-household transmission of extended-spectrum \u03b2-lactamase-producing bacteria","volume":"23","author":"Haverkate M.R.","year":"2017","unstructured":"Haverkate M.R., T.N. Platteel, A.C. Fluit, et al. 2017. Quantifying within-household transmission of extended-spectrum \u03b2-lactamase-producing bacteria. Clin. Microbiol. Infect. 23:46.e1\u2013e46.e7.","journal-title":"et al"},{"key":"e_1_3_6_35_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173510"},{"key":"e_1_3_6_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks502"},{"key":"e_1_3_6_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.12.028"},{"key":"e_1_3_6_38_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31824ea2a2"},{"key":"e_1_3_6_39_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12559"},{"key":"e_1_3_6_40_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0240314"},{"key":"e_1_3_6_41_2","doi-asserted-by":"publisher","DOI":"10.1071\/HI13013"},{"key":"e_1_3_6_42_2","first-page":"2281","article-title":"[Outbreak of multi-resistant Escherichia coli on a surgical ward: course, measures and consequences for future admissions of contaminated patients]","volume":"149","author":"van der Zwet W.C.","year":"2005","unstructured":"van der Zwet W.C., , van Riessen N., , Bergervoet P.W.M, , van der Laan J.R, , Savelkoul P.H.M, , and Sebens F.W.. 2005. [Outbreak of multi-resistant Escherichia coli on a surgical ward: course, measures and consequences for future admissions of contaminated patients]. Ned. Tijdschr. Geneeskd. 149:2281\u20132286.","journal-title":"Ned. Tijdschr. Geneeskd"},{"key":"e_1_3_6_43_2","doi-asserted-by":"publisher","DOI":"10.1086\/533475"},{"key":"e_1_3_6_44_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S205163"},{"key":"e_1_3_6_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2020.10.026"},{"key":"e_1_3_6_46_2","doi-asserted-by":"publisher","DOI":"10.1136\/vetreco-2018-000307"},{"key":"e_1_3_6_47_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz1091"},{"key":"e_1_3_6_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis581"},{"key":"e_1_3_6_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.12.024"},{"key":"e_1_3_6_50_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00293"},{"key":"e_1_3_6_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2010.02.002"},{"key":"e_1_3_6_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn293"},{"key":"e_1_3_6_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01613-20"},{"key":"e_1_3_6_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taz083"},{"key":"e_1_3_6_55_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw221"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2022.0035","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2022.0035","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2022.0035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:40:19Z","timestamp":1777668019000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/mdr.2022.0035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,1]]},"references-count":54,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,7,1]]}},"alternative-id":["10.1089\/mdr.2022.0035"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2022.0035","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,1]]}}}