{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:32:35Z","timestamp":1777923155397,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>\n                    This study aimed to identify variation in the minimum biocidal concentration (MBC) over time, comparing three commercial super-oxidized solutions with different chemical compositions. In the bactericidal assay, the following bacteria were tested:\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    (ATCC 25922),\n                    <jats:italic toggle=\"yes\">Pseudomonas aeruginosa<\/jats:italic>\n                    (ATCC 27853),\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    (ATCC 25923), and for each ATCC, one wild-type strain was used.\n                    <jats:italic toggle=\"yes\">In vitro<\/jats:italic>\n                    experiments were performed in triplicate at 0, 60, and 120 days of follow up. A commercial formulation based on sodium and chloride ions (SCSS) was tested using a standard accelerated aging protocol. Data were analyzed with the Friedman and Wilcoxon signed-rank tests. The results showed that super-oxidized solution bases of 20\u2009ppm of sodium (SSS) had a significant change in MBC at 120 days (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.001), whereas SCSS remained stable during the same period (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u20090.18). However, after accelerated aging treatment, the MBC of SCSS increased (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.001). With our proposed approach, the two SSS showed MBC variation at 120 days, whereas SCSS showed stability over time, similar to chlorhexidine, but lost its bactericidal properties after accelerated aging treatment.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2022.0212","type":"journal-article","created":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T09:22:50Z","timestamp":1677662570000},"page":"309-315","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["How Does Time Affect the Antimicrobial Activity of Super-Oxidized Commercial Antiseptic Solutions? An\n                    <i>In Vitro<\/i>\n                    Test"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8938-3615","authenticated-orcid":false,"given":"Marco S.","family":"Perez-Ayala","sequence":"first","affiliation":[{"name":"Laboratory of Microbiology, Division of Health Sciences, Department of Medicine and Nutrition, University of Guanajuato, Campus Le\u00f3n, Leon, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Division of Health Sciences, Department of Medicine and Nutrition, University of Guanajuato, Campus Le\u00f3n, Leon, Mexico."},{"name":"Regional Hospital of High Specialty of Baj\u00edo, Health Secretary, Leon, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro E.","family":"Macias","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Division of Health Sciences, Department of Medicine and Nutrition, University of Guanajuato, Campus Le\u00f3n, Leon, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brenda J.","family":"Torres-Murillo","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology, Division of Health Sciences, Department of Medicine and Nutrition, University of Guanajuato, Campus Le\u00f3n, Leon, Mexico."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,11]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"O'Neill Tackling drug-resistant infections globally J.: Final report and recommendations. 2016. 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