{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T06:45:17Z","timestamp":1781592317895,"version":"3.54.5"},"reference-count":10,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T00:00:00Z","timestamp":1690761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:p>\n                    The objective of this study was to evaluate the accuracy of the MDR Direct Flow Chip Kit for the detection of antimicrobial resistance (AMR) determinants from bacterial colonies. Ninety-two clinical isolates with known AMR determinants genotypically characterized were used. The MDR Direct Flow Chip Kit is a microarray-based assay that included 55 AMR determinants for beta-lactams (23), quinolones (13), aminoglycosides (5), macrolides (5), sulfonamides (3), colistin (2), vancomycin (2), chloramphenicol (1), and linezolid (1). The MDR Direct Flow Chip Kit correctly detects 52 of 53 AMR determinants tested. The\n                    <jats:italic toggle=\"yes\">cfr<\/jats:italic>\n                    gene (linezolid resistance) was not detected. The global sensibility, specificity, positive predictive value, and the negative predictive value calculated were 98%, 100%, 100%, and 97%. The Cohen's Kappa coefficient calculated was 0.97 [95% Confidence Interval (0.90\u20131.03)]. In conclusion, the MDR Direct Flow Chip is an accurate assay for the detection of multiple AMR determinants in one simple reaction.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2022.0264","type":"journal-article","created":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T11:07:17Z","timestamp":1679656037000},"page":"381-385","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Evaluation of the MDR Direct Flow Chip Kit for the Detection of Multiple Antimicrobial Resistance Determinants"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6373-9724","authenticated-orcid":false,"given":"\u00c1ngel","family":"Rodr\u00edguez-Villodres","sequence":"first","affiliation":[{"name":"Clinical Unit of Infectious Diseases, Microbiology and Parasitology, University Hospital Virgen del Roc\u00edo, Seville, Spain."},{"name":"Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, Seville, Spain."},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Galiana-Cabrera","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n para el fomento de la Investigaci\u00f3n Sanitaria y Biom\u00e9dica de la Comunidad Valenciana, Hospital General Universitario de Elche (Servicio de Microbiolog\u00eda), Elche, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Torres Fink","sequence":"additional","affiliation":[{"name":"Microbiology Service, Clinic University Hospital, INCLIVA Health Research Institute, Valencia, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Duran Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Clinical Unit of Infectious Diseases, Microbiology and Parasitology, University Hospital Virgen del Roc\u00edo, Seville, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Miguel","family":"Cisneros","sequence":"additional","affiliation":[{"name":"Clinical Unit of Infectious Diseases, Microbiology and Parasitology, University Hospital Virgen del Roc\u00edo, Seville, Spain."},{"name":"Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, Seville, Spain."},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain."},{"name":"Department of Medicine and University of Seville, Seville, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Lepe","sequence":"additional","affiliation":[{"name":"Clinical Unit of Infectious Diseases, Microbiology and Parasitology, University Hospital Virgen del Roc\u00edo, Seville, Spain."},{"name":"Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, Seville, Spain."},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Infecciosas (CIBERINFEC), Madrid, Spain."},{"name":"Department of Microbiology, University of Seville, Seville, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,7,31]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1703058"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000330"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00089-17"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa352"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00376-16"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2018.12.015"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0177627"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-021-04314-2"},{"key":"e_1_3_6_11_2","doi-asserted-by":"crossref","first-page":"e0172821","DOI":"10.1128\/spectrum.01728-21","article-title":"Evaluating NG-Test CARBA 5 Multiplex Immunochromatographic and Cepheid Xpert CARBA-R Assays among Carbapenem-Resistant Enterobacterales Isolates Associated with Bloodstream Infection","volume":"10","author":"Huang YT","year":"2022","unstructured":"Huang YT, , Kuo YW, , Lee NY, et al. Evaluating NG-Test CARBA 5 Multiplex Immunochromatographic and Cepheid Xpert CARBA-R Assays among Carbapenem-Resistant Enterobacterales Isolates Associated with Bloodstream Infection. Microbiol Spectr, 2022; 10:e0172821; doi: 10.1128\/spectrum.01728-21","journal-title":"Microbiol Spectr"}],"container-title":["Microbial Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/mdr.2022.0264","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2022.0264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/mdr.2022.0264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:40:47Z","timestamp":1777668047000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/mdr.2022.0264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,31]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8,1]]}},"alternative-id":["10.1089\/mdr.2022.0264"],"URL":"https:\/\/doi.org\/10.1089\/mdr.2022.0264","relation":{},"ISSN":["1076-6294","1931-8448"],"issn-type":[{"value":"1076-6294","type":"print"},{"value":"1931-8448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,31]]}}}