{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:09:10Z","timestamp":1784696950954,"version":"3.55.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n                    In 2022, we undertook a point prevalence screening study for\n                    <jats:italic toggle=\"yes\">Enterobacterales<\/jats:italic>\n                    with extended-spectrum \u03b2-lactamases (ESBLs), high-level AmpC cephalosporinases and carbapenemases, and also methicillin-resistant\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    (MRSA) and vancomycin-resistant enterococci (VRE) in a long-term care facility (LTCF) and the associated acute-care hospital Geriatrics unit in Bolzano, Northern Italy. Urine samples and rectal, inguinal, oropharyngeal, and nasal swabs were plated on selective agar plates. Metadata of the patients, including demographic data, were collected, and risk factors for colonization were determined. ESBL, AmpC, carbapenemase, and quinolone resistance genes were investigated by the HybriSpot 12 PCR AUTO System. The following colonization percentages by multidrug-resistant (MDR) bacteria have been found in LTCF residents: all MDR organisms, 59.5%; ESBL producers, 46.0% (mainly CTX-M-type enzymes); carbapenemase producers, 1.1% (one\n                    <jats:italic toggle=\"yes\">Klebsiella pneumoniae<\/jats:italic>\n                    with KPC-type); MRSA, 4.5%; VRE, 6.7%. Colonization by MDR bacteria was 18.9% for LTCF staff and 45.0% for Geriatrics unit patients. Peripheral vascular disease, the presence of any medical device, cancer, and a Katz Index of 0 were significant risk factors for colonization of LTCF residents by MDR bacteria in univariate and\/or multivariate regression analysis. To conclude, the ongoing widespread diffusion of MDR bacteria in the LTCF suggests that efforts should be strengthened on MDR screening, implementation of infection control strategies, and antibiotic stewardship programs targeting the unique aspects of LTCFs.\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                    ID: 0530250-BZ Reg01 30\/08\/2022.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2023.0019","type":"journal-article","created":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T11:19:45Z","timestamp":1688123985000},"page":"477-484","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Colonization of Residents and Staff of an Italian Long-Term Care Facility and an Adjacent Acute Care Hospital Geriatrics Unit by Multidrug-Resistant Bacteria"],"prefix":"10.1177","volume":"29","author":[{"given":"Maria Teresa","family":"Nitti","sequence":"first","affiliation":[{"name":"Reparto di Geriatria, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferisa","family":"Sleghel","sequence":"additional","affiliation":[{"name":"Reparto di Geriatria, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malgorzata","family":"Kaczor","sequence":"additional","affiliation":[{"name":"Reparto di Geriatria, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Aschbacher","sequence":"additional","affiliation":[{"name":"Laboratorio Aziendale di Microbiologia e Virologia, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Moroder","sequence":"additional","affiliation":[{"name":"Laboratorio Aziendale di Microbiologia e Virologia, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Maria","family":"Di Pierro","sequence":"additional","affiliation":[{"name":"Laboratorio Aziendale di Microbiologia e Virologia, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Piscopiello","sequence":"additional","affiliation":[{"name":"Dipartimento SCCDP, Unit\u00e0 di Microbiologia e Microbiologia clinica, Universit\u00e0 degli Studi di Pavia, Pavia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Spalla","sequence":"additional","affiliation":[{"name":"Dipartimento SCCDP, Unit\u00e0 di Microbiologia e Microbiologia clinica, Universit\u00e0 degli Studi di Pavia, Pavia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurora","family":"Piazza","sequence":"additional","affiliation":[{"name":"Dipartimento SCCDP, Unit\u00e0 di Microbiologia e Microbiologia clinica, Universit\u00e0 degli Studi di Pavia, Pavia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Migliavacca","sequence":"additional","affiliation":[{"name":"Dipartimento SCCDP, Unit\u00e0 di Microbiologia e Microbiologia clinica, Universit\u00e0 degli Studi di Pavia, Pavia, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabetta","family":"Pagani","sequence":"additional","affiliation":[{"name":"Laboratorio Aziendale di Microbiologia e Virologia, Comprensorio Sanitario di Bolzano, Bolzano, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,10,11]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1086\/592416","article-title":"SHEA\/APIC guideline: Infection prevention and control in the long-term care facility","volume":"29","author":"Smith PW","year":"2008","unstructured":"Smith PW, , Bennett G, , Bradley S, et al. SHEA\/APIC guideline: Infection prevention and control in the long-term care facility. Infect Control Hosp Epidemiol, 2008; 29:785\u2013814; doi: 10.1016\/j.ajic.2008.06.001","journal-title":"Infect Control Hosp Epidemiol"},{"key":"e_1_3_5_3_2","first-page":"1011","article-title":"Antimicrobial resistance and stewardship in long-term care settings","volume":"8","author":"Moro ML","year":"2013","unstructured":"Moro ML, , Gagliotti C. Antimicrobial resistance and stewardship in long-term care settings. Future Med, 2013; 8:1011\u20131025; doi: 10.2217\/fmb.13.75","journal-title":"Future Med"},{"key":"e_1_3_5_4_2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s13670-015-0120-2","article-title":"Colonization with multi-drug resistant organisms in nursing homes: Scope, importance, and management","volume":"4","author":"Cassone M","year":"2015","unstructured":"Cassone M, , Mody L. Colonization with multi-drug resistant organisms in nursing homes: Scope, importance, and management. Curr Geriatr Rep, 2015; 4:87\u201395; doi: 10.1007\/s13670-015-0120-2","journal-title":"Curr Geriatr Rep"},{"key":"e_1_3_5_5_2","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s13756-020-00771-0","article-title":"GLISTer (Gruppo di Lavoro per lo Studio delle Infezioni nelle Residenze Sanitarie Assistite e Strutture Assimilabili) Working Group. Recommendations for the surveillance of multidrug-resistant bacteria in Italian long-term care facilities by the GLISTer working group of the Italian Association of Clinical Microbiologists (AMCLI)","volume":"9","author":"Aschbacher R","year":"2020","unstructured":"Aschbacher R, , Pagani L, , Migliavacca R, et al. GLISTer (Gruppo di Lavoro per lo Studio delle Infezioni nelle Residenze Sanitarie Assistite e Strutture Assimilabili) Working Group. 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