{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:33:12Z","timestamp":1777923192556,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:p>\n                    A\n                    <jats:italic toggle=\"yes\">Klebsiella quasipneumoniae<\/jats:italic>\n                    subsp.\n                    <jats:italic toggle=\"yes\">similipneumoniae<\/jats:italic>\n                    strain, named S915, belonging to the ST1859 O5:KL35, and harboring the plasmid-mediated quinolone resistance\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    gene, was isolated from a soil sample cultivated with lettuce in Brazil. The core genome multilocus sequence typing analysis revealed that S915 strain was most related to a clinical strain of Brazil. Comparative genomic analysis showed that ST1859 O5:KL35 strains have been circulating in clinical settings and are closely related to multidrug resistance and multimetal tolerance. Strain S915 presented a plasmid contig co-harboring the\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    gene and tellurite tolerance operon. The region harboring the\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    gene (IS\n                    <jats:italic toggle=\"yes\">Ecp1<\/jats:italic>\n                    -\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    -\n                    <jats:italic toggle=\"yes\">araJ<\/jats:italic>\n                    -\n                    <jats:italic toggle=\"yes\">ahp<\/jats:italic>\n                    ) shared high similarity with others from infected humans, ready-to-eat dish, and food-producing animals in Brazil. This is the first report of the plasmid-mediated\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    gene in the environment. Our findings evidence the initial dissemination of the\n                    <jats:italic toggle=\"yes\">qnrE1<\/jats:italic>\n                    gene in the environment by the introduction of a clinical strain, which may be spread to different sectors, representing a One Health challenge.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2023.0075","type":"journal-article","created":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T12:20:45Z","timestamp":1688991645000},"page":"492-496","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Klebsiella quasipneumoniae<\/i>\n                    subsp.\n                    <i>similipneumoniae<\/i>\n                    ST1859 O5:KL35 from Soil: First Report of\n                    <i>qnrE1<\/i>\n                    in the Environment"],"prefix":"10.1177","volume":"29","author":[{"given":"Ralf","family":"Lopes","sequence":"first","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Pedro Rueda","family":"Furlan","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micaela Santana","family":"Ramos","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas David Rodrigues dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael da Silva","family":"Rosa","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliana Guedes","family":"Stehling","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Science, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,11]]},"reference":[{"issue":"7","key":"e_1_3_5_2_2","first-page":"e000195","article-title":"Fluoroquinolone resistance in Salmonella: Insights by whole-genome sequencing","volume":"4","author":"Cuypers WL","year":"2018","unstructured":"Cuypers WL, , Jacobs J, , Wong V, et al. 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Commun Biol, 2021; 4(1):8; doi: 10.1038\/s42003-020-01545-5","journal-title":"Commun Biol"},{"issue":"5","key":"e_1_3_5_6_2","doi-asserted-by":"crossref","first-page":"e02555","DOI":"10.1128\/AAC.02555-16","article-title":"qnrE1, a member of a new family of plasmid-located quinolone resistance genes, originated from the chromosome of Enterobacter Species","volume":"61","author":"Albornoz E","year":"2017","unstructured":"Albornoz E, , Tijet N, , De Belder D, et al. qnrE1, a member of a new family of plasmid-located quinolone resistance genes, originated from the chromosome of Enterobacter Species. 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