{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T18:21:38Z","timestamp":1782757298613,"version":"3.54.5"},"reference-count":17,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    infections have become increasingly resistant to antibiotics, including fluoroquinolones, third-generation cephalosporins (C3G), and even carbapenems. This report describes the emergence of a strain of\n                    <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                    serovar Heidelberg that produces the carbapenemase OXA 48. The strain was isolated from a stool sample taken from a newborn. Antimicrobial susceptibility testing was carried out following the recommendations of the Clinical and Laboratory Standard Institute. Whole genome sequencing was performed on MiSeq Illumina\u2122. The strain was resistant to ertapenem (minimal inhibitory concentration [MIC] = 12 \u00b5g\/mL), intermediate to imipenem (MIC = 1.5 \u00b5g\/mL), resistant to nalidixic acid, and intermediate to fluoroquinolones but was susceptible to C3G, cotrimoxazole, chloramphenicol, and colistin (MIC = 0.064 \u00b5g\/mL). The strain was identified as ST-15. The strain of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    Heidelberg ST-15 was found to have antimicrobial resistance genes, specifically\n                    <jats:italic toggle=\"yes\">blaOXA-48<\/jats:italic>\n                    , aac(6\u2032)-Iaa and\n                    <jats:italic toggle=\"yes\">fosA7<\/jats:italic>\n                    , which mediate resistance to carbapenems, aminoglycosides and fosfomycin, respectively. Additionally, mutations were detected in the\n                    <jats:italic toggle=\"yes\">gyrA<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">parC.<\/jats:italic>\n                    Three plasmid replicon type IncL, IncX1, and Col156 have been identified. The strain has the potential to cause an epidemic. The genomic analysis of the strain allowed us to understand the mechanisms of resistance. Preventing the spread of\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    carbapenemase-producing strains is crucial, particularly in hospital settings. Epidemiological measures are necessary to achieve this goal.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2023.0287","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T03:44:56Z","timestamp":1730864696000},"page":"509-512","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Emergence of\n                    <i>Salmonella enterica<\/i>\n                    Serovar Heidelberg Producing OXA 48 Carbapenemase in Eastern Algeria"],"prefix":"10.1177","volume":"30","author":[{"given":"Selma","family":"Bouheraoua","sequence":"first","affiliation":[{"name":"Department of Bacteriology, Pasteur Institute of Algeria, Algiers, Algeria."},{"name":"Faculty of pharmacy, University of Algiers 1, Algiers, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdesselam","family":"Lezzar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Hospital Center of Constantine, Constantine, Algeria."},{"name":"Faculty of Medicine, University of Constantine, Constantine, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farida","family":"Assaous","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Pasteur Institute of Algeria, Algiers, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chafia","family":"Bentchouala","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Hospital Center of Constantine, Constantine, Algeria."},{"name":"Faculty of Medicine, University of Constantine, Constantine, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadjia","family":"Mahrane","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Pasteur Institute of Algeria, Algiers, Algeria."},{"name":"Faculty of pharmacy, University of Algiers 1, Algiers, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaddour","family":"Benlabed","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Hospital Center of Constantine, Constantine, Algeria."},{"name":"Faculty of Medicine, University of Constantine, Constantine, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassiba","family":"Tali Maamar","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Pasteur Institute of Algeria, Algiers, Algeria."},{"name":"Faculty of pharmacy, University of Algiers 1, Algiers, Algeria."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,2]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/318457"},{"issue":"6","key":"e_1_3_4_3_2","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1017\/S0195941700061555","article-title":"Nosocomial salmonellosis","volume":"6","author":"Weikel CS","year":"1985","unstructured":"Weikel CS, , Guerrant RL. Nosocomial salmonellosis. Infect Control, 1985; 6(6):218\u2013220; doi: 10.1017\/s0195941700061555","journal-title":"Infect Control"},{"key":"e_1_3_4_4_2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1471-2334-4-35","article-title":"Nosocomial outbreak of neonatal Salmonella enterica serotype Enteritidis meningitis in a rural hospital in northern Tanzania","volume":"4","author":"Vaagland H","year":"2004","unstructured":"Vaagland H, , Blomberg B, , Kr\u00fcger C, et al. Nosocomial outbreak of neonatal Salmonella enterica serotype Enteritidis meningitis in a rural hospital in northern Tanzania. 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J Clin Microbiol, 2014; 52(2):627\u2013631; doi: 10.1128\/JCM.02422-13","journal-title":"J Clin Microbiol"},{"issue":"6","key":"e_1_3_4_6_2","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ijantimicag.2004.03.006","article-title":"Expanded-spectrum cephalosporin resistance in non-typhoid Salmonella","volume":"23","author":"Miriagou V","year":"2004","unstructured":"Miriagou V, , Tassios PT, , Legakis NJ, et al. Expanded-spectrum cephalosporin resistance in non-typhoid Salmonella. Int J Antimicrob Agents, 2004; 23(6):547\u2013555; doi: 10.1016\/j.ijantimicag.2004.03.006","journal-title":"Int J Antimicrob Agents"},{"key":"e_1_3_4_7_2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jgar.2022.03.023","article-title":"A nosocomial salmonellosis outbreak caused by blaOXA-48 carrying, extensively drug-resistant Salmonella enterica Serovar Goldcoast in a hospital respiratory care ward in Taiwan","volume":"29","author":"Chen CM","year":"2022","unstructured":"Chen CM, , Tang HL, , Ke SC, et al. A nosocomial salmonellosis outbreak caused by blaOXA-48 carrying, extensively drug-resistant Salmonella enterica Serovar Goldcoast in a hospital respiratory care ward in Taiwan. J Glob Antimicrob Resist, 2022; 29:331\u2013338; doi: 10.1016\/j.jgar.2022.03.023","journal-title":"J Glob Antimicrob Resist"},{"key":"e_1_3_4_8_2","volume-title":"Performance standards for Antimicrobial Susceptibility Testing","author":"CLSI","year":"2022","unstructured":"CLSI. 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