{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:34:24Z","timestamp":1777923264173,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>\n                    Antimicrobial resistance is currently considered a public health threat. Carbapenems are antimicrobials for hospital use, and Enterobacterales resistant to these \u03b2-lactams have spread alarmingly in recent years, especially those that cause health care-associated infections. The\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>KPC<\/jats:sub>\n                    gene is considered one of the most important genetic determinants disseminated by plasmids, promoting horizontal gene transfer. This study describes, for the first time in Ecuador, and worldwide, the presence of a\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>KPC-2<\/jats:sub>\n                    gene in an isolate of\n                    <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                    serovar Infantis from a clinical sample. Through whole-genome sequencing, we characterized the genetic determinants of antimicrobial resistance in this\n                    <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                    ST-32 strain. Our results showed the presence of several resistance genes, including\n                    <jats:italic toggle=\"yes\">bla<\/jats:italic>\n                    <jats:sub>CTX-M-65<\/jats:sub>\n                    , and a conjugative plasmid Kpn-WC17-007-03 that may be responsible for the horizontal transference of these resistance mechanisms.\n                  <\/jats:p>","DOI":"10.1089\/mdr.2024.0072","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T11:53:07Z","timestamp":1733485987000},"page":"502-508","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["<i>Salmonella enterica<\/i>\n                    Serovar Infantis KPC-2 Producer: First Isolate Reported in Ecuador"],"prefix":"10.1177","volume":"30","author":[{"given":"Fernando","family":"Villavicencio","sequence":"first","affiliation":[{"name":"National Reference Center for Antimicrobial Resistance RAM, National Institute for Public Health Research, INSPI, Quito, Ecuador."},{"name":"Facultad de Medicina Veterinaria y Agronom\u00eda, Carrera de Medicina Veterinaria, Universidad UTE, Av. Mariana de Jes\u00fas, Quito, Ecuador."},{"name":"Faculty of Health Sciences, SEK International University of Ecuador, Alberto Einstein and 5ta Transversal, Quito, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviana","family":"Alb\u00e1n","sequence":"additional","affiliation":[{"name":"Institute of Microbiology, San Francisco de Quito University, Cumbay\u00e1, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Sat\u00e1n","sequence":"additional","affiliation":[{"name":"National Reference Center for Antimicrobial Resistance RAM, National Institute for Public Health Research, INSPI, Quito, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidaleisy","family":"Quintana","sequence":"additional","affiliation":[{"name":"Jos\u00e9 Carrasco Arteaga Hospital, Cuenca, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wladimir","family":"Enr\u00edquez","sequence":"additional","affiliation":[{"name":"National Reference Center for Antimicrobial Resistance RAM, National Institute for Public Health Research, INSPI, Quito, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Jaramillo","sequence":"additional","affiliation":[{"name":"National Reference Center for Antimicrobial Resistance RAM, National Institute for Public Health Research, INSPI, Quito, Ecuador."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Flores","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias de la Vida, Universidad de las Fuerzas Armadas ESPE, Sangolqu\u00ed, Ecuador."},{"name":"Facultad de Ciencias de la Ingenier\u00eda e Industrias, Centro de Investigaci\u00f3n de Alimentos, Universidad UTE, Av. 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