{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T19:41:38Z","timestamp":1777923698338,"version":"3.51.4"},"reference-count":36,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T00:00:00Z","timestamp":1600992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Metabolic Syndrome and Related Disorders"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>To determine the association of waist-to-height ratio (WHtR), metabolic syndrome (MetS), and carotid atherosclerosis (CAS) in individuals with a high risk of stroke.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We performed a cross-sectional analysis of 9605 study responders from eight urban area communities in Northern China. Height, weight, waist circumference, blood pressure (BP), and blood lipid were measured. Information of population characteristics, smoking status, alcohol consumption, physical activity, and diet were determined by validated questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 9605 study responders were included in this study. The average age was 60\u2009\u00b1\u20099 years with 5911 (61.5%) patients being females. The prevalence of MetS and CAS was 26.2% and 75.1%, respectively. WHtR was significantly associated with CAS using our final adjusted model [odds ratio (OR): 1.233, 95% confidence interval (CI): 1.096\u20131.378]. The association of CAS with hypertension and hyperglycemia were statistically significant among factors that constitute MetS. Additional risk factors affecting the development of CAS included age, previous stroke, and smoking history (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>WHtR was determined to perform better compared with other traditional indicators for correlating CAS. We believe that WHtR is a better indicator for the early identification of CAS in individuals with a high risk of stroke. This will facilitate the early detection and intervention of CAS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/met.2020.0003","type":"journal-article","created":{"date-parts":[[2020,6,26]],"date-time":"2020-06-26T14:47:06Z","timestamp":1593182826000},"page":"381-388","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association of Waist-to-Height Ratio, Metabolic Syndrome, and Carotid Atherosclerosis in Individuals with a High Risk of Stroke: A Cross-Sectional Study of 9605 Study Participants"],"prefix":"10.1177","volume":"18","author":[{"given":"Li","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Neurology, Dongfang Hospital, The Second Clinical Medical College of Beijing University of Chinese Medicine, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoxin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongfang Hospital, The Second Clinical Medical College of Beijing University of Chinese Medicine, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinran","family":"Xie","sequence":"additional","affiliation":[{"name":"Beijing Institute of Traditional Chinese Medicine, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Wei","sequence":"additional","affiliation":[{"name":"Beijing University of Chinese Medicine, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qihui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dongfang Hospital, The Second Clinical Medical College of Beijing University of Chinese Medicine, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunling","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-014-0139-2"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-015-0096-2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-018-0935-9"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.03.009"},{"key":"e_1_3_3_6_2","article-title":"Prospective associations between beverage intake during the midlife and subclinical carotid atherosclerosis: The Study of Women's Health Across the Nation","volume":"14","author":"Wang D","year":"2019","unstructured":"Wang D, , Karvonen-Gutierrez CA, , Jackson EA, et al. 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