{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T18:15:38Z","timestamp":1788459338361,"version":"build-2803163510"},"reference-count":69,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Metabolic Syndrome and Related Disorders"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>The metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease (CVD). Prediabetes is defined by either impaired glucose tolerance or by one of the more sensitive or more stringent criterion for impaired fasting glucose (IFG) or HbA1c levels that have been promulgated over the years. IFG is one of the risk factors for CVD included in the definition of the MetS. However, there is very little evidence that IFG is independently associated with CVD regardless of which criterion is used for its diagnosis. The CVD risk of the MetS is related to the other risk factors of central obesity, hypertension, elevated triglyceride, and low high-density lipoprotein cholesterol levels. If the components of the MetS are supposed to be risk factors for CVD, the dysglycemia of prediabetes should not be included in its definition.<\/jats:p>","DOI":"10.1089\/met.2023.0005","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T08:48:52Z","timestamp":1681289332000},"page":"197-204","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Prediabetes in the Metabolic Syndrome: Guilt by Association"],"prefix":"10.1177","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9194-8857","authenticated-orcid":false,"given":"Mayer B.","family":"Davidson","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Charles R. Drew University, Los Angeles, California, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,12]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.24.6.585"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.28.12.1039"},{"key":"e_1_3_4_4_2","doi-asserted-by":"crossref","unstructured":"Jarrett RJ Keen H Hypoglycaemia and diabetes mellitus Lancet 1976;ii:1009\u20131012.","DOI":"10.1016\/S0140-6736(76)90844-8"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)91489-2"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6940.1323"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)92274-6"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.7.1183"},{"key":"e_1_3_4_9_2","unstructured":"World Health Organization. Definition Diagnosis and Classification of Diabetes Mellitus and Its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. World Health Organization: Geneva; 1999."},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540150048030"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.36.4.523"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.17.5.436"},{"key":"e_1_3_4_13_2","unstructured":"Gordon T. Glucose Tolerance of Adults United States 1960\u20131962: Diabetes Prevalence and Results of Glucose Tolerance Test by Age and Sex. Vital and Health Statistics. Series 11 No.2. U.S. Government Printing Office: Washington DC; 1964."},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.2337\/diab.14.7.413"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2017.10.003"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.11.3160"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-2368"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050080"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.02.026"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-2263"},{"key":"e_1_3_4_21_2","unstructured":"World Health Organization. Definition Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia: Report of a WHO\/IDF Consultation. Report of a WHO Consultation. World Health Organization: Geneva; 2006."},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2174"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-9033"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-S062"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2010.09.022"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj:e4624"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2011.03.012"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-1954"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00418345"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/000456329803500107"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69420-8"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-010-1985-4"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60525-X"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12920"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13789"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-4895-0"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CDO"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-2030"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-1457"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-1238"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908359"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)01118-8"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.25.10.1851"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60484-9"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.1873"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-1683"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.07.002"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.10.2910"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5953"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-1213"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001250051249"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.7.1728"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.28.11.2756"},{"key":"e_1_3_4_54_2","author":"Kanaya AM","unstructured":"Kanaya AM, , Herrington D, , Vittinghoff E, et al. Impaired fasting glucose and cardiovascular outcomes in postmenopausal women with coronary artery disease. Ann Intern Med 2005:142:813\u2013820.","journal-title":"Ann Intern Med"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.09.038"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-0587"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.3.688"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.22.6.920"},{"key":"e_1_3_4_59_2","author":"Nakagami T","unstructured":"Nakagami T, , the DECODA Study Group. Hyperglycaemia and mortality from all causes and from cardiovascular disease in five populations of Asian origin. Diabetologia 2004:47:385\u2013394.","journal-title":"Diabetologia"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.16.1910"},{"key":"e_1_3_4_61_2","author":"Davidson MB","unstructured":"Davidson MB, , Kahn RA. A reappraisal of prediabetes. J Clin Endocrinol Metab 2016,101:2628\u20132635.","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-141-6-200409210-00006"},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-004-1643-9"},{"key":"e_1_3_4_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.03.022"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2010.01.019"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-2010"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-2412"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc15-1078"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012512"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2021.01.200146"}],"container-title":["Metabolic Syndrome and Related Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/met.2023.0005","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/met.2023.0005","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/met.2023.0005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T20:55:25Z","timestamp":1777668925000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/met.2023.0005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":69,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1089\/met.2023.0005"],"URL":"https:\/\/doi.org\/10.1089\/met.2023.0005","relation":{},"ISSN":["1540-4196","1557-8518"],"issn-type":[{"value":"1540-4196","type":"print"},{"value":"1557-8518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5]]}}}