{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T12:49:26Z","timestamp":1789649366403,"version":"4.0.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neurotrauma"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>\n                    This study examined whether peripheral vision reaction time (PVRT) in patients with mild traumatic brain injury (mTBI) correlated with white matter abnormalities in centroaxial structures and impairments in neuropsychological testing. Within 24\u2009h after mTBI, crossed reaction times (CRT), uncrossed reaction times (URT), and crossed\u2013uncrossed difference (CUD) were measured in 23 patients using a laptop computer that displayed visual stimuli predominantly to either the left or the right visual field of the retina. The CUD is a surrogate marker of the interhemispheric transfer time (ITT). Within 7 days after the injury, patients received a diffusion tensor-MRI (DTI) scan and a battery of neuropsychological tests. Nine uninjured control subjects received similar testing. Patients 18\u201350 years of age were included if they had a post-resuscitation Glasgow Coma Scale &gt;13 and an injury mechanism compatible with mTBI. Healthy controls were either age- and gender-matched family members of the TBI patients or healthy volunteers. CUD deficits &gt;2 standard deviations (SD) were seen in 40.9% of patients. The CUD of injured patients correlated with mean diffusivity (MD) (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.001, \u03c1\u2009=\u2009\u22120.811) in the posterior corpus callosum. Patients could be stratified on the basis of CUD on the Stroop 1, Controlled Oral Word Association Test (COWAT), and the obsessive-compulsive component of the Basic Symptom Inventory tests. These studies suggest that the PVRT indirectly measures white matter integrity in the posterior corpus callosum, a brain region frequently damaged by mTBI.\n                  <\/jats:p>","DOI":"10.1089\/neu.2016.4670","type":"journal-article","created":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T02:01:25Z","timestamp":1481162485000},"page":"1539-1545","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Measurement of Peripheral Vision Reaction Time Identifies White Matter Disruption in Patients with Mild Traumatic Brain Injury"],"prefix":"10.1177","volume":"34","author":[{"given":"Kyle B.","family":"Womack","sequence":"first","affiliation":[{"name":"University of Texas Southwestern Medical Center"},{"name":"University of Texas Southwestern Medical Center"},{"name":"The University of Texas at Dallas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Paliotta","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy F.","family":"Strain","sequence":"additional","affiliation":[{"name":"The University of Texas at Dallas"},{"name":"Washington University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnson S.","family":"Ho","sequence":"additional","affiliation":[{"name":"State University of New York-Downstate Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosef","family":"Skolnick","sequence":"additional","affiliation":[{"name":"State University of New York-Downstate Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Lytton","sequence":"additional","affiliation":[{"name":"State University of New York-Downstate Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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