{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:34:42Z","timestamp":1777926882252,"version":"3.51.4"},"reference-count":85,"publisher":"SAGE Publications","issue":"17","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurotrauma"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1089\/neu.2016.4696","type":"journal-article","created":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T14:55:20Z","timestamp":1522335320000},"page":"2125-2135","source":"Crossref","is-referenced-by-count":41,"title":["Glibenclamide Produces Region-Dependent Effects on Cerebral Edema in a Combined Injury Model of Traumatic Brain Injury and Hemorrhagic Shock in Mice"],"prefix":"10.1177","volume":"35","author":[{"given":"Ruchira M.","family":"Jha","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Neurosurgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley J.","family":"Molyneaux","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Neurosurgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Travis C.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica S.","family":"Wallisch","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seo-Young","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel","family":"Poloyac","sequence":"additional","affiliation":[{"name":"Department of Pharmacy and Therapeutics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent A.","family":"Vagni","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keri L.","family":"Janesko-Feldman","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keito","family":"Hoshitsuki","sequence":"additional","affiliation":[{"name":"Department of Pharmacy and Therapeutics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Beth","family":"Minnigh","sequence":"additional","affiliation":[{"name":"Department of Pharmacy and Therapeutics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick M.","family":"Kochanek","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Safar Center for Resuscitation Research, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Clinical and Translational Science Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."},{"name":"Department of Anesthesia, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-52892-6.00001-5"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1097\/00001199-200609000-00001"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02689-1"},{"key":"B4","first-page":"366","volume":"3","author":"Chestnut R.M.","year":"1995","journal-title":"New Horiz"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000837"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.73.5.0688"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2007.22.5.2"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1996.84.1.0097"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.06.046"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.5.720"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.898190"},{"key":"B12","first-page":"74","volume":"28","author":"Feldmann H.","year":"1979","journal-title":"Acta Neurochir. Suppl. (Wien)"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199907000-00008"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1977.47.4.0503"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.56.4.0498"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2005.05.031"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1405"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067514"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/nm1390"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0b013e3181fbf6d6"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2009.1021"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-24-08568.2003"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.428219"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-17-06512.2001"},{"key":"B25","first-page":"273","volume":"76","author":"Portella G.","year":"2000","journal-title":"Acta Neurochir. Suppl."},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2008.0512"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2013.104"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318206b1fa"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2011.2303"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2009.1021"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.04.040"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2007.10.010"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-199603000-00009"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.522409"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2011.11.048"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199302000-00006"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2005.103.4.0707"},{"key":"B38","first-page":"289","volume":"71","author":"Katayama Y.","year":"1998","journal-title":"Acta Neurochir. Suppl."},{"key":"B39","first-page":"323","volume":"86","author":"Katayama Y.","year":"2003","journal-title":"Acta Neurochir. Suppl. (Wien)"},{"key":"B40","first-page":"925","volume":"15","author":"Xu Z.-M.","year":"2016","journal-title":"J. Neurotrauma"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1007\/3-211-30714-1_29"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076904"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041229"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00180-5"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0128782"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2015.05.006"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3675"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1002\/glia.22581"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23602"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-011-0087-4"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2011.07211.x"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.3171\/2009.11.JNS081052"},{"key":"B53","first-page":"214","volume":"89","author":"Langfitt T.W.","year":"1964","journal-title":"Trans. Am. Neurol. Assoc."},{"key":"B54","first-page":"49","volume":"62","author":"Langfitt T.W.","year":"1966","journal-title":"W. V. Med. J."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1966.24.1.0047"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/91.2.281"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2000.93.2.0183"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-9334-1_1"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.91"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1999.16.583"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70055-8"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00455"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-06932-3"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2016.4514"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1995.12.1015"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1186\/s12868-016-0295-2"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000001215"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.06.005"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2013.3274"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2014.3439"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-17"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2014.06.020"},{"key":"B73","first-page":"119","volume":"32","author":"Jha R.M.","year":"2015","journal-title":"J. Neurotrauma"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002079"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3000522"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000048215.36747.D1"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2008.120"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.572644"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001093"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.166"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2012.02.010"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-013-9923-1"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3015"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-015-0432-3"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.5812\/traumamon.25113"}],"container-title":["Journal of Neurotrauma"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/neu.2016.4696","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/neu.2016.4696","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:26:27Z","timestamp":1777674387000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/neu.2016.4696"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":85,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1089\/neu.2016.4696"],"URL":"https:\/\/doi.org\/10.1089\/neu.2016.4696","relation":{},"ISSN":["0897-7151","1557-9042"],"issn-type":[{"value":"0897-7151","type":"print"},{"value":"1557-9042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]}}}