{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T06:13:31Z","timestamp":1788416011053,"version":"build-2803163510"},"reference-count":42,"publisher":"SAGE Publications","issue":"20","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neurotrauma"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>\n                    Sports-related concussion (SRC) can exert serious acute and long-term consequences on brain microstructure, function, and behavioral outcomes. We aimed to quantify the alterations in white matter (WM) microstructure and global network organization, and the decrements in behavioral and cognitive outcomes from pre-season to post-concussion in youth athletes who experienced SRC. We also aimed to evaluate whether wearing a jugular compression neck collar, a device designed to mitigate brain \u201cslosh\u201d injury, would mitigate the pre-season to post-concussion alterations in neuroimaging, behavioral, and cognitive outcomes. A total of 488 high school football and soccer athletes (14-18 years old) were prospectively enrolled and assigned to the non-collar group (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009237) or the collar group (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009251). The outcomes of the study were the pre-season to post-concussion neuroimaging, behavioral, and cognitive alterations. Forty-six participants (non-collar:\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200924; collar:\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200922) were diagnosed with a SRC during the season. Forty of these 46 athletes (non-collar:\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200920; collar:\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200920) completed neuroimaging assessment. Significant pre-season to post-concussion alterations in WM microstructural integrity and brain network organization were found in these athletes (corrected\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.05). The alterations were significantly reduced in collar-wearing athletes compared to non-collar-wearing athletes (corrected\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Concussion and collar main effects were identified for some of the behavioral and cognitive outcomes, but no collar by SRC interaction effects were observed in any outcomes. In summary,\n                    <jats:bold>y<\/jats:bold>\n                    oung athletes exhibited significant WM microstructural and network organizational, and cognitive alterations following SRC. The use of the jugular vein compression collar showed promising evidence to reduce these alterations in high school contact sport athletes.\n                  <\/jats:p>","DOI":"10.1089\/neu.2021.0141","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T13:37:28Z","timestamp":1628602648000},"page":"2811-2821","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["High School Sports-Related Concussion and the Effect of a Jugular Vein Compression Collar: A Prospective Longitudinal Investigation of Neuroimaging and Neurofunctional Outcomes"],"prefix":"10.1177","volume":"38","author":[{"given":"Weihong","family":"Yuan","sequence":"first","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jed A.","family":"Diekfuss","sequence":"additional","affiliation":[{"name":"Emory Sports Performance and Research Center, Flowery Branch, Georgia, USA."},{"name":"Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim D.","family":"Barber Foss","sequence":"additional","affiliation":[{"name":"Emory Sports Performance and Research Center, Flowery Branch, Georgia, USA."},{"name":"Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan A.","family":"Dudley","sequence":"additional","affiliation":[{"name":"Pediatric Neuroimaging Research Consortium, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Leach","sequence":"additional","affiliation":[{"name":"Division of Radiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Narad","sequence":"additional","affiliation":[{"name":"Division of Behavioral Medicine &amp; Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A.","family":"DiCesare","sequence":"additional","affiliation":[{"name":"Division of Sports Medicine, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Bonnette","sequence":"additional","affiliation":[{"name":"Division of Sports Medicine, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery N.","family":"Epstein","sequence":"additional","affiliation":[{"name":"Division of Radiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Division of Behavioral Medicine &amp; Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelsey","family":"Logan","sequence":"additional","affiliation":[{"name":"Division of Sports Medicine, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."},{"name":"Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mekibib","family":"Altaye","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Epidemiology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, Ohio, USA."},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory D.","family":"Myer","sequence":"additional","affiliation":[{"name":"Emory Sports Performance and Research Center, Flowery Branch, Georgia, USA."},{"name":"Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia, USA."},{"name":"Emory Sports Medicine Center, Atlanta, Georgia, USA."},{"name":"The Micheli Center for Sports Injury Prevention, Waltham, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,12]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2010.08.006"},{"key":"e_1_3_6_3_2","first-page":"597","article-title":"American Academy of Pediatrics","volume":"126","author":"Halstead M.E.","year":"2010","unstructured":"Halstead M.E., and Walter K.D, ; 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(2020). Baseline vs. cross-sectional MRI of concussion: distinct brain patterns in white matter and cerebral blood flow. Sci. Rep. 10, 1643.","journal-title":"cross-sectional MRI of concussion: distinct brain patterns in white matter and cerebral blood flow. Sci. Rep"},{"key":"e_1_3_6_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws048"},{"key":"e_1_3_6_43_2","first-page":"232596711351158","article-title":"Altered brain microstructure in association with repetitive subconcussive head impacts and the potential protective effect of jugular vein compression: a longitudinal study of female soccer athletes","volume":"1","author":"Myer G.D.","year":"2018","unstructured":"Myer G.D., , Barber Foss K., , Thomas S., , Galloway R., , DiCesare C.A., , Dudley J., , Gadd B., , Leach J., , Smith D., , Gubanich P., , Meehan W.P., , 3rd Altaye, , M., Lavin P., , and Yuan W. (2018). 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