{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:43:12Z","timestamp":1792510992889,"version":"4.5.0"},"reference-count":105,"publisher":"SAGE Publications","issue":"1-2","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neurotrauma"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    Mental health conditions and concussion history reported by a collegiate athlete may contribute to prolonged recovery and symptom severity after concussion. This work examined the potential associations among concussion history, preexisting conditions, and sex relative to initial symptom severity and recovery duration following sport-related concussion (SRC) in a cohort of Division 1 National Collegiate Athletic Association athletes. This prospective cohort study analyzed symptom severity, recovery, and return-to-play (RTP) times reported post-SRC using data collected as part of the Pac-12 Concussion Assessment, Research and Education Affiliated Program and Health Analytics Program. Health history questionnaires that included self-reported history of preexisting conditions were completed at baseline. When consented athletes were diagnosed with a concussion, daily postconcussion symptom scores were evaluated until an athlete was clinically determined to be asymptomatic. Generalized linear and Cox proportional hazards models were used to determine associations between preexisting conditions and recovery and RTP times. Ninety-two concussions met inclusion criteria. Notable differences in initial symptom severity existed between females and males who had mood disorders (effect size [\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    ] = 0.51) and attention-deficit hyperactivity disorder (ADHD;\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    = 0.93). The number of previous concussions was a strong predictor of athletes reporting preexisting mood disorders, depression, anxiety, and ADHD (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = 0.008\u20130.04). Females with \u22652 previous concussions required more days to RTP than males (\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    = 0.31\u20130.72). Weekly recovery and RTP probabilities substantially differed between athletes who did or did not have learning disorders (LDs; hazard ratio [HR]\n                    <jats:sub>Recovery<\/jats:sub>\n                    = 0.32, HR\n                    <jats:sub>RTP<\/jats:sub>\n                    = 0.22,\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    = 1.96\u20132.30) and ADHD (HR\n                    <jats:sub>Recovery<\/jats:sub>\n                    = 3.38, HR\n                    <jats:sub>RTP<\/jats:sub>\n                    = 2.74,\n                    <jats:italic toggle=\"yes\">d<\/jats:italic>\n                    = 1.71\u20134.14). Although no association existed between concussion history and acute symptom severity, collegiate athletes with a history of concussion had higher probabilities of reporting depression, mood disorders, anxiety, and ADHD. Having ADHD or LDs likely strongly affects time to recovery and RTP for collegiate athletes.\n                  <\/jats:p>","DOI":"10.1089\/neu.2024.0201","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T03:15:08Z","timestamp":1727234108000},"page":"57-70","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Influence of Preexisting Conditions and Concussion History on Postconcussion Symptom Severity and Recovery Time in Collegiate Athletes"],"prefix":"10.1177","volume":"42","author":[{"given":"Niki A.","family":"Konstantinides","sequence":"first","affiliation":[{"name":"Department of Integrative Physiology, University of Colorado\u2014Boulder, Boulder, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean M.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Cumberland Biological and Ecological Researchers, Longmont, 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