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While pharmacological treatments are typically used for CPTH, they frequently cause side effects and have limited effectiveness, leading individuals with CPTH to be unsatisfied with current treatment options and to seek nonpharmacological options. Acupuncture has been identified as a potential treatment option; however, the evidence in this population remains limited. The overall goal of this study was to examine the effect of a once weekly (e.g., low dose) versus twice weekly (e.g., high dose) of acupuncture treatment on CPTH in individuals with mTBI. Thirty-eight individuals were randomized to receive either 5 or 10 acupuncture treatments using a standard protocol over 5 weeks. The protocol consisted of 14 points using traditional acupuncture and 4 points using electroacupuncture. Headache outcomes, safety, treatment adherence, sleep quality, and quality of life (QOL) were assessed. The results showed that while there were no differences between dose groups for any of the outcomes assessed, acupuncture significantly reduced the number of headache days and headache pain intensity in individuals with CPTH. There were no significant changes in acute medication use or sleep quality. While there were some QOL improvements identified, these results should be interpreted with caution. Overall, acupuncture was shown to be safe and well-tolerated in people with CPTH after mTBI, and five acupuncture treatments using a standardized protocol shows promise in providing headache relief for this population.<\/jats:p>","DOI":"10.1089\/neu.2024.0212","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T08:23:56Z","timestamp":1726820636000},"page":"19-32","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Acupuncture Treatment for Chronic Post-Traumatic Headache in Individuals with Mild Traumatic Brain Injury: A Pilot Study"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5939-4081","authenticated-orcid":false,"given":"Amanda A.","family":"Herrmann","sequence":"first","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota, USA."},{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ella A.","family":"Chrenka","sequence":"additional","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota, USA."},{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia G.","family":"Bouwens","sequence":"additional","affiliation":[{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."},{"name":"Healing Response Acupuncture and Functional Neurology, Lake Elmo, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellie K.","family":"Tansey","sequence":"additional","affiliation":[{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."},{"name":"Regions Hospital, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayla A.","family":"Wolf","sequence":"additional","affiliation":[{"name":"Healing Response Acupuncture and Functional Neurology, Lake Elmo, Minnesota, USA."},{"name":"Carrick Institute, Cape Canaveral, Florida, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerri W.","family":"Chung","sequence":"additional","affiliation":[{"name":"Minneapolis VA Healthcare System, Minneapolis, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marny T.","family":"Farrell","sequence":"additional","affiliation":[{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."},{"name":"Regions Hospital, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha J.","family":"Sherman","sequence":"additional","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota, USA."},{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleta L.","family":"Svitak","sequence":"additional","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota, USA."},{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leah R.","family":"Hanson","sequence":"additional","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota, USA."},{"name":"HealthPartners Institute Neuroscience Research Center, St. Paul, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1179\/2042618613y.0000000053"},{"key":"e_1_3_7_3_2","unstructured":"Faul M Xu L Wald MM et al. 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