{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:26:23Z","timestamp":1787498783248,"version":"build-2736575974"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.liebertpub.com\/nv\/resources-tools\/text-and-data-mining-policy\/121\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Network and Systems Medicine"],"published-print":{"date-parts":[[2020,8,1]]},"DOI":"10.1089\/nsm.2020.0005","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T23:35:13Z","timestamp":1596497713000},"page":"105-121","source":"Crossref","is-referenced-by-count":15,"title":["Combining Gene\u2013Disease Associations with Single-Cell Gene Expression Data Provides Anatomy-Specific Subnetworks in Age-Related Macular Degeneration"],"prefix":"10.1177","volume":"3","author":[{"given":"Philip J.","family":"Luthert","sequence":"first","affiliation":[{"name":"UCL Institute of Ophthalmology, and NIHR Moorfields Biomedical Research Centre, University College London, London, United Kingdom."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Kiel","sequence":"additional","affiliation":[{"name":"Systems Biology Ireland and UCD Charles Institute of Dermatology, School of Medicine, University College Dublin, Dublin, Ireland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(13)70145-1"},{"key":"B2","author":"Khanna S","journal-title":"BMJ Open Ophthalmol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.06.018"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3448"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41514-019-0039-5"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2014.11.001"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1914143116"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12917-9"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1093\/database\/bau012"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M500279-MCP200"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260419"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1131"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2188-x"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1101\/2020.01.19.905109"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1038\/srep41835"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.5.3218"},{"key":"B17","volume":"55","author":"Salami A","year":"2019","journal-title":"Medicina (Kaunas)"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201343968"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201600373R"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204318"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2014.00044"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M412730200"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201404399"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1096\/fj.13-229740"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6625"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M000008200"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2006.04.001"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.28899"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.14914"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biodatasci-080917-013356"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11262-1"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1186\/gm315"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1038\/75556"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/S0369-8114(02)00336-X"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)62248-1"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2019.10.008"}],"container-title":["Network and Systems Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.liebertpub.com\/doi\/full-xml\/10.1089\/nsm.2020.0005","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.liebertpub.com\/doi\/pdf\/10.1089\/nsm.2020.0005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T04:05:56Z","timestamp":1772424356000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/nsm.2020.0005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,8,1]]}},"alternative-id":["10.1089\/nsm.2020.0005"],"URL":"https:\/\/doi.org\/10.1089\/nsm.2020.0005","relation":{},"ISSN":["2690-5949"],"issn-type":[{"value":"2690-5949","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,1]]}}}