{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T03:35:51Z","timestamp":1779161751456,"version":"3.51.4"},"reference-count":51,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy, Immunology, and Pulmonology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>The rising prevalence of food allergy and specifically peanut allergy has had significant implications for affected patients, families, and society. The current standard of care remains strict avoidance and the use of emergency medications for accidental ingestions. There is recent evidence-based information to suggest that one approach to preventing peanut allergy lies in early introduction of peanut. This represents a paradigm shift from previous recommendations and has led to updated guidelines in the United States, Europe, and Australasia on the introduction of potentially allergenic foods in the infant diet. This new approach to prevention has some practical obstacles and challenges associated with its implementation. There is also growing interest in the role of maintaining a healthy skin barrier in prevention of sensitization and food allergy. Other approaches, including pro- and prebiotics, prenatal maternal dietary avoidance, breastfeeding, and the use of specific formulas, have not shown reproducibly favorable results. As children with peanut allergy are unlikely to outgrow their food allergy, early oral immunotherapy in those with established peanut allergy is being investigated with the hopes of altering the natural history of an otherwise lifelong disease.<\/jats:p>","DOI":"10.1089\/ped.2017.0826","type":"journal-article","created":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T16:08:49Z","timestamp":1516637329000},"page":"2-8","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Preventing Peanut Allergy"],"prefix":"10.1177","volume":"31","author":[{"given":"Meng","family":"Chen","sequence":"first","affiliation":[{"name":"University of California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Welch","sequence":"additional","affiliation":[{"name":"Rady Children's Hospital"},{"name":"Allergy & Asthma Medical Group & Research Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Laubach","sequence":"additional","affiliation":[{"name":"University of California"},{"name":"Rady Children's Hospital"},{"name":"Allergy & Asthma Medical Group & Research Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-0204"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2015.36.3819"},{"key":"e_1_3_3_4_2","first-page":"483","article-title":"Early introduction of allergenic foods for the prevention of food allergy from an Asian perspective-An Asia Pacific Association of Pediatric Allergy, Respirology & Immunology (APAPARI) consensus statement","volume":"117","author":"Tham EH","year":"2017","unstructured":"Tham EH, , Shek LP-C, , Van Bever HP, , Vichyanond P, , Ebisawa M, , Wong GW, et al. Early introduction of allergenic foods for the prevention of food allergy from an Asian perspective-An Asia Pacific Association of Pediatric Allergy, Respirology & Immunology (APAPARI) consensus statement. Pediatr Allergy Immunol, 2017; 117:483.","journal-title":"Pediatr Allergy Immunol"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.115480"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-1210"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.10.029"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1180"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.112129"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.02.005"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2013.2376"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.106.2.346"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.03.029"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.08.039"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3022"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414850"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514209"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514210"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.06.001"},{"key":"e_1_3_3_20_2","unstructured":"World Health Organization. Nutrition: complementary feeding. Available at: www.who.int\/nutrition\/topics\/complementary_feeding\/en (September 15 2017)."},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.09.039"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.10.010"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001454"},{"key":"e_1_3_3_24_2","unstructured":"Australasian Society of Clinical Immunology and Allergy. ASCIA Information on how to introduce solid foods to babies for allergy prevention. Available at: www.allergy.org.au\/patients\/allergy-prevention\/ascia-how-to-introduce-solid-foods-to-babies (September 15 2017)."},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.13100"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.04.011"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.0922"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.07.019"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-4-4-144"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.3390\/children2030382"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013536"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.07.041"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2011.3.2.67"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.11.032"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2005.02260.x"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.358"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.10.007"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.10.049"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.07.060"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.3345\/kjp.2013.56.9.369"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09889.x"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002562"},{"key":"e_1_3_3_43_2","first-page":"CD006474","article-title":"Prebiotics in infants for prevention of allergy","volume":"3","author":"Osborn DA","year":"2013","unstructured":"Osborn DA, , Sinn JKH. Prebiotics in infants for prevention of allergy. Cochrane Database Syst Rev, 2013; 3:CD006474.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3038.1999.101010.x"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.12398"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2003.00264.x"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.02.023"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1111\/apa.13132"},{"key":"e_1_3_3_49_2","first-page":"CD003664","article-title":"Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants","volume":"4","author":"Osborn DA","year":"2006","unstructured":"Osborn DA, , Sinn J. Formulas containing hydrolysed protein for prevention of allergy and food intolerance in infants. Cochrane Database Syst Rev, 2006; 4:CD003664.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.04.021"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.13124"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.05.027"}],"container-title":["Pediatric Allergy, Immunology, and Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/ped.2017.0826","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ped.2017.0826","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/ped.2017.0826","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:13:38Z","timestamp":1777677218000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/ped.2017.0826"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1089\/ped.2017.0826"],"URL":"https:\/\/doi.org\/10.1089\/ped.2017.0826","relation":{},"ISSN":["2151-321X","2151-3228"],"issn-type":[{"value":"2151-321X","type":"print"},{"value":"2151-3228","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}