{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T18:28:19Z","timestamp":1788805699280,"version":"build-2803163510"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Allergy, Immunology, and Pulmonology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"\n Introduction:<\/jats:title>\n In 2019, an alarming number of cases coined as e-cigarette, or vaping, product use-associated lung injury (EVALI) were described in adolescents ranging from mild respiratory distress to fulminant respiratory failure. Limited data have been published on outcomes at short-term follow-up. We aimed to describe pulmonary manifestations, function, and radiologic findings after corticosteroid therapy in a cohort of adolescent patients.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A retrospective chart analysis of all patients presenting to our institution between July 2019 and December 2019 with EVALI was conducted. Patients who had pulmonary follow-up were included. Spirometry was performed before discharge from the hospital and during outpatient follow-up. A paired\n t<\/jats:italic>\n -test was used to compare serial spirometry data between visits.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Eight patients (6 males) were included. Two patients required intubation with mechanical ventilation, 2 required bilevel positive airway pressure, and 3 required oxygen supplementation. All patients received glucocorticoids (3 receiving pulse dosing). Initial spirometry revealed decreased forced expiratory volume in one second and forced vital capacity with clinically and statistically significant improvement at follow-up (mean follow-up was 46.5 days). Radiographic manifestations also improved after vaping was discontinued.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n In our cohort of patients with EVALI, at short-term follow-up, all normalized their spirometry parameters and showed clinical resolution of symptoms.<\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/ped.2020.1270","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T12:24:06Z","timestamp":1616070246000},"page":"23-29","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Improvement in Pulmonary Function Following Discontinuation of Vaping or E-Cigarette Use in Adolescents with EVALI"],"prefix":"10.1177","volume":"34","author":[{"given":"Stanley A.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Sayad","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naga Jaya Smitha","family":"Yenduri","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin Yuqi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert Paul","family":"Guillerman","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold J.","family":"Farber","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911614"},{"key":"e_1_3_4_3_2","unstructured":"Outbreak of Lung Injury Associated with the Use of E-Cigarette or Vaping Products. Centers for Disease Control and Prevention. Available at https:\/\/www.cdc.gov\/tobacco\/basic_information\/e-cigarettes\/severe-lung-disease.html (accessed September1 2020)."},{"key":"e_1_3_4_4_2","article-title":"Harms of E-cigarettes: what the healthcare provider needs to know","author":"Farber HJ","unstructured":"Farber HJ, , Conrado Pacheco GM, , Galiatsasos P, et al. Harms of E-cigarettes: what the healthcare provider needs to know. Ann Am Thorac Soc 2020. 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