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We report a case of DRESS syndrome in a 17-year-old female caused by itraconazole, confirmed by patch testing, that required treatment with both corticotherapy and cyclosporine. Our case highlights the importance of clinical suspicion of this syndrome in pediatric age and the novelty of an antifungal drug being identified as the culprit.<\/jats:p>","DOI":"10.1089\/ped.2023.0066","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T12:50:36Z","timestamp":1695214236000},"page":"143-146","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Drug Rash with Eosinophilia and Systemic Symptoms Syndrome Caused by Itraconazole in a 17-Year-Old Girl"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8681-0914","authenticated-orcid":false,"given":"Helena","family":"Pires Pereira","sequence":"first","affiliation":[{"name":"Allergy and Clinical Immunology Department, Coimbra University Hospital Center, Coimbra, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iolanda Alen","family":"Coutinho","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Department, Coimbra University Hospital Center, Coimbra, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Carrapatoso","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Department, Coimbra University Hospital Center, Coimbra, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Todo-Bom","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Department, Coimbra University Hospital Center, Coimbra, Portugal."},{"name":"Allergy and Clinical Immunology Department, Faculty of Medicine, University of Coimbra, Coimbra, Portugal."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,12,15]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10184287"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030704"},{"issue":"3","key":"e_1_3_3_4_2","first-page":"66","article-title":"Drug reaction with eosinophilia and systemic symptoms (DRESS) in children","volume":"90","author":"Mori F","year":"2019","unstructured":"Mori F, , Caffarelli C, , Caimmi S, et al. 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