{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:44:22Z","timestamp":1790790262949,"version":"4.1.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["PHAGE: Therapy, Applications, and Research"],"published-print":{"date-parts":[[2024,6,1]]},"abstract":"<jats:p>\n                    Bacterial canker, caused by\n                    <jats:italic toggle=\"yes\">Pseudomonas syringae<\/jats:italic>\n                    , is a devastating disease of stone fruit trees worldwide. The bacterium has a broad host range and a high capacity for adaptation and dissemination, owing to its high mutation rate and horizontal gene transfer. Traditional control methods based on copper compounds and antibiotics have resulted in the development of resistance in the bacterial population. Thus, alternative approaches are needed, such as phage therapy. This study aimed to characterize the physicochemical and biological properties of novel\n                    <jats:italic toggle=\"yes\">Pseudomonas syringae<\/jats:italic>\n                    pv.\n                    <jats:italic toggle=\"yes\">syringae<\/jats:italic>\n                    (\n                    <jats:italic toggle=\"yes\">Pss<\/jats:italic>\n                    )-specific phages isolated from the soils of northwestern Iran. Seventy-five phage isolates were obtained, and their host range was determined against various bacterial pathogens. Five phages exhibiting the highest lytic activity against\n                    <jats:italic toggle=\"yes\">Pss<\/jats:italic>\n                    and a narrow host range were selected for subsequent analysis. The stability of the selected phages was assessed under different conditions such as ultraviolet irradiation, temperature, pH, NaCl concentration, and chloroform exposure. The selected phages demonstrated significant effectiveness\n                    <jats:italic toggle=\"yes\">in\u00a0vivo<\/jats:italic>\n                    , exerting substantial suppression on the population of\n                    <jats:italic toggle=\"yes\">Pss<\/jats:italic>\n                    . This reduction was observed for both individual phages and when the phages were utilized as a mixture. The findings indicate that phages have the potential to be used as biocontrol agents in agriculture.\n                  <\/jats:p>","DOI":"10.1089\/phage.2023.0023","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T06:49:42Z","timestamp":1712213382000},"page":"99-106","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Physicochemical Characterization of Novel Bacteriophages of\n                    <i>Pseudomonas syringe<\/i>\n                    from Northwest Iran"],"prefix":"10.1177","volume":"5","author":[{"given":"Zahra","family":"Zaer-Anaqz","sequence":"first","affiliation":[{"name":"Department of Plant Protection, Faculty of Agriculture, University of Tabriz, Tabriz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2872-8290","authenticated-orcid":false,"given":"Reza","family":"Khakvar","sequence":"additional","affiliation":[{"name":"Department of Plant Protection, Faculty of Agriculture, University of Tabriz, Tabriz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Abolghasem","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Tabriz, Tabriz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2513-5361","authenticated-orcid":false,"given":"Hossein","family":"Bannazadeh Baghi","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davoud","family":"Koolivand","sequence":"additional","affiliation":[{"name":"Department of Plant Protection, Faculty of Agriculture, University of Zanjan, Zanjan, Iran."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,6,21]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1094\/PD-91-0004"},{"key":"e_1_3_6_3_2","first-page":"1","article-title":"Characterization of culturable epiphytic and endophytic bacteria of Prunus spp. and their potential for plant growth promotion and antagonistic activity against bacterial canker disease","volume":"1","author":"Vasebi Y","year":"2023","unstructured":"Vasebi Y, , Khakvar R, , Vinatzer BA. Characterization of culturable epiphytic and endophytic bacteria of Prunus spp. and their potential for plant growth promotion and antagonistic activity against bacterial canker disease. J Plant Pathol, 2023; 1:1\u20138.","journal-title":"J Plant Pathol"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/ppa.12834"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.phyto.45.062806.094411"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.201300951"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms7090286"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033227"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12223-015-0411-1"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/07060661.2011.588250"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2009.07.012"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/03235408.2020.1745487"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/07060660709507448"},{"key":"e_1_3_6_14_2","first-page":"1","article-title":"Evaluation of bacteriophages in the biocontrol of Pseudomonas syringae pv. syringae isolated from cankers on sweet cherry (Prunus avium L.) in Turkey","volume":"31","author":"Akbaba M","year":"2021","unstructured":"Akbaba M, , Ozaktan H. Evaluation of bacteriophages in the biocontrol of Pseudomonas syringae pv. syringae isolated from cankers on sweet cherry (Prunus avium L.) in Turkey. Egyptian J Bio Pest Control, 2021; 31:1\u20131.","journal-title":"Egyptian J Bio Pest Control"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/aem.45.6.1890-1898.1983"},{"issue":"1","key":"e_1_3_6_16_2","first-page":"84","article-title":"Characterization of bacteriophages of Pseudomonas syringae pv. tomato","volume":"61","author":"Prior SE","year":"2007","unstructured":"Prior SE, , Andrews AJ, , Nordeen RO. Characterization of bacteriophages of Pseudomonas syringae pv. tomato. JArkansas Acad Sci, 2007; 61(1):84\u201389.","journal-title":"JArkansas Acad Sci"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcab.2019.101167"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00279"},{"key":"e_1_3_6_19_2","first-page":"2019010132","article-title":"Isolation and characterization of bacteriophages with lytic activity against virulent Escherichia coli O157: H7: Potential bio-control agents","author":"Ateba CN","year":"2019","unstructured":"Ateba CN, , Akindolire MA. Isolation and characterization of bacteriophages with lytic activity against virulent Escherichia coli O157: H7: Potential bio-control agents. 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