{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:19:38Z","timestamp":1790648378494,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2008,12]]},"abstract":"\n Objective:<\/jats:title>\n The purpose of this placebo-controlled study was to investigate the therapeutic effects of the 830-nm diode laser on carpal tunnel syndrome (CTS).<\/jats:p>\n <\/jats:sec>\n \n Background Data:<\/jats:title>\n Many articles in the literature have demonstrated that low-level laser therapy (LLLT) may help to alleviate various types of nerve pain, especially for CTS treatment. We placed an 830-nm laser directly above the transverse carpal ligament, which is between the pisiform and navicular bones of the tested patients, to determine the therapeutic effect of LLLT.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Thirty-six patients with mild to moderate degree of CTS were randomly divided into two groups. The laser group received laser treatment (10 Hz, 50% duty cycle, 60 mW, 9.7 J\/cm\n 2<\/jats:sup>\n , at 830 nm), and the placebo group received sham laser treatment. Both groups received treatment for 2 wk consisting of a 10-min laser irradiation session each day, 5 d a week. The therapeutic effects were assessed on symptoms and functional changes, and with nerve conduction studies (NCS), grip strength assessment, and with a visual analogue scale (VAS), soon after treatment and at 2-wk follow-up.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Before treatment, there were no significant differences between the two groups for all assessments (\n p<\/jats:italic>\n > 0.05). The VAS scores were significantly lower in the laser group than the placebo group after treatment and at follow-up (\n p<\/jats:italic>\n < 0.05). After 2 wk of treatment, no significant differences were found in grip strengths or for symptoms and functional assessments (\n p<\/jats:italic>\n > 0.05). However, there were statistically significant differences in these variables at 2-wk follow-up (\n p<\/jats:italic>\n < 0.05). Regarding the findings of NCS, there was no statistically significant difference between groups after treatment and at 2-wk follow-up.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n LLLT was effective in alleviating pain and symptoms, and in improving functional ability and finger and hand strength for mild and moderate CTS patients with no side effects.<\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/pho.2007.2234","type":"journal-article","created":{"date-parts":[[2008,11,23]],"date-time":"2008-11-23T12:34:23Z","timestamp":1227443663000},"page":"551-557","source":"Crossref","is-referenced-by-count":61,"title":["Carpal Tunnel Syndrome Treated with a Diode Laser: A Controlled Treatment of the Transverse Carpal Ligament"],"prefix":"10.1177","volume":"26","author":[{"given":"Wen-Dien","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei, Taiwan."},{"name":"Department of Rehabilitation Medicine, Da Chien General Hospital, Miaoli, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jih-Huah","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Ming Chuan University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe-Air","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Bio-Industrial Mechatronics Engineering, National Taiwan University, Taipei, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yu","family":"Yeh","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Chun Shan Medical University, Taichung, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Tsung","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine, Da Chien General Hospital, Miaoli, Taiwan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2008,12]]},"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2007.2234","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2007.2234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:26:57Z","timestamp":1777678017000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/pho.2007.2234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["10.1089\/pho.2007.2234"],"URL":"https:\/\/doi.org\/10.1089\/pho.2007.2234","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,12]]}}}