{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:20:45Z","timestamp":1790648445831,"version":"4.1.0"},"reference-count":0,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2009,2]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    We have determined optimal laser dosimetric parameters in comparison with polychromatic light-emitting diodes (LEDs) that can speed up healing in four animal models: non-diabetic oval full-thickness wounds, diabetic oval full-thickness wounds, non-diabetic burns, and diabetic burns in Sprague-Dawley rats.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Materials and Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    This series of studies used 532-, 633-, 810-, 980-, and 10,600-nm lasers (visible to far infrared) and polychromatic LED clusters (510\u2013872 nm, visible to infrared) as photon sources. Sprague-Dawley rats (n = 893) were used; however, animals that died before and during the experiments from anesthesia accidents and for any other reason were excluded from statistical analysis.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    The improvements seen (&gt;10% improvement of impairment) show that phototherapy with the 633-nm laser is quite promising for alleviating diabetic wound and burn healing, and exhibited the best results with 38.5% and 53.4% improvements, respectively.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusion:<\/jats:italic>\n                    <\/jats:bold>\n                    In this induced-diabetes model, wound and burn healing were improved by 40.3% and 45%, respectively, in 633-nm laser dosimetry experiments, and diabetic wound and burn healing was accelerated by phototherapy. This indicates that the healing rate was normalized in the phototherapy-treated diabetic rats. In view of these interesting findings, 633-nm laser therapy given three times per week at 4.71 J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    per dose for diabetic burns, and three times per week at 2.35 J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    per dose for diabetic wound healing are recommended as actual doses for human clinical trials, especially after major surgery in those with impaired healing, such as diabetics and the elderly.\n                  <\/jats:p>","DOI":"10.1089\/pho.2008.2406","type":"journal-article","created":{"date-parts":[[2009,2,4]],"date-time":"2009-02-04T15:59:16Z","timestamp":1233763156000},"page":"127-135","source":"Crossref","is-referenced-by-count":54,"title":["Laser Therapy Converts Diabetic Wound Healing to Normal Healing"],"prefix":"10.1177","volume":"27","author":[{"given":"Farouk A.H.","family":"Al-Watban","sequence":"first","affiliation":[{"name":"Laser Medicine Research Section, Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,2]]},"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2008.2406","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2008.2406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:28:41Z","timestamp":1777678121000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/pho.2008.2406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["10.1089\/pho.2008.2406"],"URL":"https:\/\/doi.org\/10.1089\/pho.2008.2406","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}