{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:16:00Z","timestamp":1777929360259,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background and Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    Stevens\u2013Johnson syndrome (SJS) is a life-threatening dermatosis characterized by epidermal sloughing and stomatitis. We report the case of a 7-year-old boy in whom laser phototherapy (LPT) was highly effective in reversing the effects of an initial episode of SJS that had apparently developed in association with treatment with phenobarbital for a seizure disorder. The patient was first seen in the intensive care unit (ICU) of our institution with fever, cutaneous lesions on his extremities, trunk, face, and neck; mucosal involvement of his genitalia and eyes (conjunctivitis); ulcerative intraoral lesions; and swollen, crusted, and bleeding lips. He reported severe pain at the sites of his intraoral and skin lesions and was unable to eat, speak, swallow, or open his mouth.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Materials and Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Trying to prevent and minimize secondary infections, gastric problems, pain, and other complications, the patient was given clindamycin, ranitidine, dipyrone, diphenhydramine (Benadryl) drops, and morphine. In addition, he was instructed to use bicarbonate solution and Ketoconazole (Xylogel) in the oral cavity. Because of the lack of progress of the patient, the LPT was selected.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    At 5 days after the initial session of LPT, the patient was able to eat gelatin, and on the following day, the number and severity of his intraoral lesions and his labial crusting and swelling had diminished. By 6 days after his initial session of LPT, most of the patient's intraoral lesions had disappeared, and the few that remained were painless; the patient was able to eat solid food by himself and was removed from the ICU. Ten sessions of LPT were conducted in the hospital. The patient underwent three further and consecutive sessions at the School of Dentistry, when complete healing of his oral lesions was observed.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusion:<\/jats:italic>\n                    <\/jats:bold>\n                    The outcome in this case suggests that LPT may be a new adjuvant modality for SJS complications.\n                  <\/jats:p>","DOI":"10.1089\/pho.2009.2671","type":"journal-article","created":{"date-parts":[[2010,10,25]],"date-time":"2010-10-25T22:36:29Z","timestamp":1288046189000},"page":"67-69","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Laser Phototherapy for Stevens\u2013Johnson Syndrome: A Case Report"],"prefix":"10.1177","volume":"29","author":[{"given":"Alyne","family":"Sim\u00f5es","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia Moreira","family":"de Freitas","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina Stella","family":"Bello\u2013Silva","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Tun\u00e9r","sequence":"additional","affiliation":[{"name":"Swedish Laser Medical Society","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"de Paula Eduardo","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"965","DOI":"10.2165\/00002018-200225130-00006","article-title":"Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in children: a review of 10 years' experience","volume":"25","author":"Forman R.","year":"2002","unstructured":"Forman R., , Koren G., , Shear N.H. 2002. Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis in children: a review of 10 years' experience. Drug Saf, 25:965\u2013972.","journal-title":"Drug Saf"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2007.07.202"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb06976.x"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-007-0238-7"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2008.2300"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20758"},{"key":"e_1_3_3_8_2","first-page":"414","volume-title":"Ten lectures on basic science of laser phototherapy","author":"Karu T.","year":"2007","unstructured":"Karu T. 2007. Ten lectures on basic science of laser phototherapy. Gr\u00e4ngesberg: Sweeden Prima Books, 414."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2009.00078.x"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10107"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20008"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s10103-007-0531-1","article-title":"Effect of low-intensity laser therapy on mast cell degranulation in human oral mucosa","volume":"24","author":"Sawasaki I.","year":"2009","unstructured":"Sawasaki I., , Geraldo-Martins V.R., , Ribeiro M.S., , Marques M.M. 2009. Effect of low-intensity laser therapy on mast cell degranulation in human oral mucosa. Lasers Med Sci, 24:113\u2013116.","journal-title":"Lasers Med Sci"},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1089\/clm.1993.11.185","article-title":"Effect of low-power He-Ne laser on deformability of stored human erythrocytes","volume":"11","author":"Iijima K.","year":"1993","unstructured":"Iijima K., , Shimoyama N., , Shimoyama M., , Mizuguchi T. 1993. Effect of low-power He-Ne laser on deformability of stored human erythrocytes. J Clin Laser Med Surg, 11:185\u2013189.","journal-title":"J Clin Laser Med Surg"},{"key":"e_1_3_3_14_2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1529-8027.2007.00114.x","article-title":"830\u2009nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830\u2009nm laser","volume":"12","author":"Chow R.T.","year":"2007","unstructured":"Chow R.T., , David M.A., , Armati P.J. 2007. 830\u2009nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830\u2009nm laser. J Peripher Nerv Syst, 12:28\u201339.","journal-title":"J Peripher Nerv Syst"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20583"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2004.22.537"}],"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/pho.2009.2671","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2009.2671","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2009.2671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:31:04Z","timestamp":1777678264000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/pho.2009.2671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1089\/pho.2009.2671"],"URL":"https:\/\/doi.org\/10.1089\/pho.2009.2671","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}