{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:17:31Z","timestamp":1777929451143,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    This article aimed to study the effect of LED Phototherapy (LED-PHT) (\u03bb630\u2009nm or \u03bb850\u2009nm) on mast cells on the dorsum of the tongue of rodents.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background Data:<\/jats:italic>\n                    <\/jats:bold>\n                    Vasodilatation is one of the reported effects of laser light on tissues. Laser light is able to induce the release of mediators responsible for vasodilatation, such as those produced by mast cells. Mast cells are also related to some diseases such as hay fever.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Sixty Wistar rats were divided into three groups: I, Control; II, IR-LED (\u03bb850\u2009nm, 21.9\u2009J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    , 73 sec; and III, red-LED (\u03bb630\u2009nm, 21.9\u2009J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    , 73\u2009sec). The specimens were taken after, 20, 45, and 60\u2009min following irradiation. The specimens were routinely processed; stained with toluidine blue; and then total, degranulated, and non-degranulated mast cells were counted and statistical analysis performed.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    Both LED irradiated subjects showed significant difference when compared to the control subjects on the total number mast cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001, ANOVA), degranulated mast cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001, ANOVA), and non-degranulated mast cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001, ANOVA). Comparing the two groups of LED irradiated subjects, significant difference was observed regarding the total number of cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001, paired\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    -test) and degranulated mast cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt;0.001, paired\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    -test) with a greater number of these cells noted in the IR-LED group. On the other hand, Red-LED irradiated subjects showed a significantly greater number of non-degranulated mast cells (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    =0.001, paired\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    -test).\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    Our results lead us to conclude that both red and IR-LED light caused increased mast cell degranulation and that IR-LED light resulted in a greater number of mast cells.\n                  <\/jats:p>","DOI":"10.1089\/pho.2011.3035","type":"journal-article","created":{"date-parts":[[2011,7,26]],"date-time":"2011-07-26T09:57:36Z","timestamp":1311674256000},"page":"767-771","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Effect of LED Red and IR Photobiomodulation in Tongue Mast Cells in Wistar Rats: Histological Study"],"prefix":"10.1177","volume":"29","author":[{"given":"Juliana Santos","family":"de Carvalho Monteiro","sequence":"first","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana Carla Pires Sampaio","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"de F\u00e1tima Ferreira Lima","sequence":"additional","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Augusto Cardoso","family":"Sousa","sequence":"additional","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Luiz Barbosa","family":"Pinheiro","sequence":"additional","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]},{"name":"University of S\u00e3o Paulo","place":["Brazil"]},{"name":"Institute of Biomedical Engineering, Unicastelo, S\u00e3o Jos\u00e9 dos Campos","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Nunes","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Federal University of Bahia","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,11]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"Robbins: structural and functional pathology [Robbins: patologia estrutural e funcional]","author":"Cotran R.","year":"2000","unstructured":"Cotran R., , Kumar V., , Collins T. 2000. 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