{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:16:55Z","timestamp":1787242615161,"version":"build-2736575974"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    The aim of this study was to evaluate the clinical and microbiological results of treatment with the Er:YAG laser and topical gaseous ozone application as adjuncts to initial periodontal therapy in chronic periodontitis (CP) patients.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background data:<\/jats:italic>\n                    <\/jats:bold>\n                    Although many studies have evaluated the effectiveness of the Er:YAG laser as an adjunct to initial periodontal therapy, few studies have focused on the use of gaseous ozone as an adjunct.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Materials and methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Thirty patients with CP were randomly divided into three parallel groups, each composed of 10 individuals with at least four teeth having at least one approximal site with a probing depth (PD) of \u22655\u2009mm and a sulcus bleeding index (SBI) \u22652 in each quadrant. Groups of patients received: (1) Scaling and root planing (SRP)+Er:YAG laser; (2) SRP+topical gaseous ozone; or (3) SRP alone. The microbiological and clinical parameters were monitored at day 0 and day 90.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    At the end of the observation period, statistically significant improvements in clinical parameters were observed within each group. Parallel to the clinical changes, all treatments reduced the number of total bacteria and the proportion of obligately anaerobic microorganisms. Although intergroup comparisons of microbiological parameters showed no significant differences, clinical findings, including attachment gain and PD reduction, were found to be statistically significant in favor of the SRP+Er:YAG laser group.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    Although statistically nonsignificant, the fact that the obligate anaerobic change was mostly observed in the SRP+Er:YAG laser group, and a similar decrease was noted in the SRP+topical gaseous ozone group, shows that ozone has an antimicrobial effect equivalent to that of the Er:YAG laser.\n                  <\/jats:p>","DOI":"10.1089\/pho.2012.3379","type":"journal-article","created":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T10:27:03Z","timestamp":1370514423000},"page":"293-298","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":47,"title":["Evaluation of the Clinical and Antimicrobial Effects of the Er:YAG Laser or Topical Gaseous Ozone as Adjuncts to Initial Periodontal Therapy"],"prefix":"10.1177","volume":"31","author":[{"given":"Sel\u00e7uk","family":"Y\u0131lmaz","sequence":"first","affiliation":[{"name":"Yeditepe University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serdar","family":"Algan","sequence":"additional","affiliation":[{"name":"Yeditepe University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hare","family":"Gursoy","sequence":"additional","affiliation":[{"name":"Yeditepe University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulku","family":"Noyan","sequence":"additional","affiliation":[{"name":"Ac'badem Hospital","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar Eren","family":"Kuru","sequence":"additional","affiliation":[{"name":"Marmara University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanju","family":"Kadir","sequence":"additional","affiliation":[{"name":"Marmara University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,6]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"1237","article-title":"Research, Science and Therapy Committee of the American Academy of Periodontology. Diagnosis of periodontal diseases","volume":"74","author":"Armitage G.C.","year":"2003","unstructured":"Armitage G.C. 2003. Research, Science and Therapy Committee of the American Academy of Periodontology. Diagnosis of periodontal diseases. J. Periodontol., 74:1237\u201347.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/154405910408301010"},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1590\/S1678-77572011000100015","article-title":"Ultramorphology of the root surface subsequent to hand-ultrasonic simultaneous instrumentation during non-surgical periodontal treatments","volume":"19","author":"Aspriello S.D.","year":"2011","unstructured":"Aspriello S.D., , Piemontese M., , Levrini L., , Salvatore S. 2011. Ultramorphology of the root surface subsequent to hand-ultrasonic simultaneous instrumentation during non-surgical periodontal treatments. An in vitro study. J. Appl. Oral Sci., 19:74\u201381.","journal-title":"An in vitro study. J. Appl. Oral Sci."},{"key":"e_1_3_2_5_2","first-page":"494","volume-title":"Clinical Periodontology","author":"Novak M.J.","year":"2009","unstructured":"Novak M.J., , Novak K.F. 2009. Chronic Periodontitis. Clinical Periodontology, 10th Carranza F.A. Philadelphia: W.B. Saunders Co., 494\u2013499.","edition":"10"},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1902\/jop.1988.59.8.493","article-title":"Ultrastructural observation on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth","volume":"59","author":"Adriaens P.A.","year":"1958","unstructured":"Adriaens P.A., , Edwards C.A., , De Boever J.A., , Loesche W.J. 1958. Ultrastructural observation on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth. J. Periodontol., 59:493\u2013503.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01461.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0757.2004.03679.x","article-title":"Lasers in nonsurgical periodontal therapy","volume":"36","author":"Aoki A.","year":"2004","unstructured":"Aoki A., , Miyuki S.K., , Watanabe H., , Ishikawa I. 2004. Lasers in nonsurgical periodontal therapy. Periodontol., 2000; 36:59\u201397.","journal-title":"Periodontol."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2010.2762"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1007\/s002160050133","article-title":"Early problems in the analysis and the determination of ozone","volume":"357","author":"Burns D.T.","year":"1997","unstructured":"Burns D.T. 1997. Early problems in the analysis and the determination of ozone. Fresenius J. Anal. Chem., 357:178\u2013183.","journal-title":"Fresenius J. Anal. Chem."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.5005\/jcdp-9-4-75"},{"key":"e_1_3_2_12_2","doi-asserted-by":"crossref","first-page":"151","DOI":"10.4103\/0976-9668.92318","article-title":"Ozone therapy in dentistry: a strategic review J","volume":"2","author":"Saini R.","year":"2011","unstructured":"Saini R. 2011. Ozone therapy in dentistry: a strategic review J. Nat. Sci. Biol. Med., 2:151\u2013153.","journal-title":"Nat. Sci. Biol. Med."},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2011.00825.x"},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy (II) Correlation between oral hygiene and periodontai condition","volume":"11","author":"Silness J.","year":"1964","unstructured":"Silness J., , Loe H. 1964. Periodontal disease in pregnancy (II) Correlation between oral hygiene and periodontai condition. Acta Odontol. Scand., 11:121\u2013135.","journal-title":"Acta Odontol. Scand."},{"key":"e_1_3_2_15_2","first-page":"107","article-title":"Gingival sulcus bleeding: a leading symptom in initial gingivitis","volume":"15","author":"M\u00fchlemann H.R","year":"1971","unstructured":"M\u00fchlemann H.R, , Son S. 1971. Gingival sulcus bleeding: a leading symptom in initial gingivitis. Helv. Odont. Acta, 15:107\u2013112.","journal-title":"Helv. Odont. Acta"},{"key":"e_1_3_2_16_2","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1600-051X.1997.tb00485.x","article-title":"A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients","volume":"24","author":"Noyan U.","year":"1997","unstructured":"Noyan U., , Yilmaz S., , Kuru B., , Kadir T., , Acar O., , Buget E. 1997. A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients. J. Clin. Periodontol., 24:158\u2013165.","journal-title":"J. Clin. Periodontol."},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1902\/jop.2001.72.3.361","article-title":"Periodontal treatment with an Er:YAG laser compared to scaling and root planing. A controlled clinical study","volume":"72","author":"Schwarz F.","year":"2001","unstructured":"Schwarz F., , Sculean A., , Georg T., , Reich E. 2001. Periodontal treatment with an Er:YAG laser compared to scaling and root planing. A controlled clinical study. J. Periodontol., 72:361\u2013367.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.300105.x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1902\/jop.2007.060460","article-title":"Effect of Er:YAG laser compared to ultrasonic scaler in periodontal treatment: a 2-year follow-up split-mouth clinical study","volume":"78","author":"Crespi R.","year":"2007","unstructured":"Crespi R., , Cappare P., , Toscanelli I., , Gherlone E., , Romanos G.E. 2007. Effect of Er:YAG laser compared to ultrasonic scaler in periodontal treatment: a 2-year follow-up split-mouth clinical study. J. Periodontol., 78:1195\u20131200.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_20_2","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1902\/jop.2003.74.5.590","article-title":"Treatment with an Er:YAG lazer or scaling and root planing. A 2-year follow-up split-mouth study","volume":"74","author":"Schwarz F.","year":"2003","unstructured":"Schwarz F., , Sculean A., , Berakdar M., , Georg T., , Reich E., , Becker J. 2003. Treatment with an Er:YAG lazer or scaling and root planing. A 2-year follow-up split-mouth study. J. Periodontol., 74:590\u2013596.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2009.2705"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.70796"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-011-0515-1"},{"key":"e_1_3_2_24_2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1902\/jop.2006.77.1.111","article-title":"Short-term clinical and microbiologic effects of pocket debridement with an Er:YAG laser during periodontal maintenance","volume":"77","author":"Tomasi C.","year":"2006","unstructured":"Tomasi C., , Schander K., , Dahlen G., , Wennstrom J.L. 2006. Short-term clinical and microbiologic effects of pocket debridement with an Er:YAG laser during periodontal maintenance. J. Periodontol., 77:111\u2013118.","journal-title":"J. Periodontol."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00052.x"}],"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/pho.2012.3379","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2012.3379","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2012.3379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:35:30Z","timestamp":1777678530000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/pho.2012.3379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["10.1089\/pho.2012.3379"],"URL":"https:\/\/doi.org\/10.1089\/pho.2012.3379","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}