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A GaAlAs diode laser [780\u2009nm, 30\u2009mW continuous wave (CW), 0.785\u2009cm\n                    <jats:sup>2<\/jats:sup>\n                    , 38.2 mW\/cm\n                    <jats:sup>2<\/jats:sup>\n                    ] was applied in contact with four points perpendicularly to the skin over the carpal tunnel area for 90\u2009sec per point (2.7\u2009J, 3.4\u2009J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    \/point). Both groups were treated five times per week, once a day over 2 weeks, followed by 10 treatments every other day for 3 weeks, that is, for a total of 20 treatments. Clinical assessment, including visual analogue scale (VAS) pain rating, Tinel's sign, and median nerve conduction studies (NCSs) were evaluated before, and 3 weeks after, the last LLLT treatment.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    Significant reduction in pain, reduction in the percentage of patients with a positive Tinel's sign, and shortening of sensory and motor latency time in the NCS examination was observed in the experimental LLLT group (but not in the control group).\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    This study has observed and documented the statistically significant short-term effects of LLLT on CTS patients in comparison with a placebo group. The results support this conclusion, especially if the LLLT is applied in the earlier stages of CTS, and with mild to moderate cases.\n                  <\/jats:p>","DOI":"10.1089\/pho.2013.3563","type":"journal-article","created":{"date-parts":[[2014,6,6]],"date-time":"2014-06-06T14:16:10Z","timestamp":1402064170000},"page":"336-344","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":43,"title":["Placebo-Controlled Investigation of Low-Level Laser Therapy to Treat Carpal Tunnel Syndrome"],"prefix":"10.1177","volume":"32","author":[{"given":"Milica","family":"Lazovic","sequence":"first","affiliation":[{"name":"Institute for Rehabilitation","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivera","family":"Ilic-Stojanovic","sequence":"additional","affiliation":[{"name":"Institute for Rehabilitation","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirjana","family":"Kocic","sequence":"additional","affiliation":[{"name":"Clinical Center Nis","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Zivkovic","sequence":"additional","affiliation":[{"name":"Clinical Center Nis","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marija","family":"Hrkovic","sequence":"additional","affiliation":[{"name":"Institute for Rehabilitation","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Radosavljevic","sequence":"additional","affiliation":[{"name":"Institute for Rehabilitation","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp013018"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0712(01)00002-6"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.88.10.1447"},{"key":"e_1_3_2_5_2","unstructured":"Kimura J. 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