{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T13:05:35Z","timestamp":1787231135444,"version":"build-2736575974"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background:<\/jats:italic>\n                    <\/jats:bold>\n                    Sporotrichosis is a fungal infection caused by\n                    <jats:italic toggle=\"yes\">Sporothrix schenckii<\/jats:italic>\n                    complex, usually restricted to the skin, subcutaneous cellular tissue, and adjacent lymphatic vessels. Antimicrobial photodynamic therapy (aPDT) could be a good alternative to manage localized, superficial infections.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Case report:<\/jats:italic>\n                    <\/jats:bold>\n                    A 65-year-old African woman was diagnosed with a fixed cutaneous sporotrichosis on her left arm, treated with itraconazol and oral terbinafine with partial improvement. Topical 16% methyl aminolevulinate (MAL, Metvix\n                    <jats:sup>\u00ae<\/jats:sup>\n                    )-PDT was used without success.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    An\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    photoinactivation test with the isolated microorganism revealed phenothiazinium salts to be more effective than MAL.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    PDT with intralesional 1% methylene blue (MB) in combination with intermittent low doses of itraconazole obtained complete microbiological and clinical response.\n                  <\/jats:p>","DOI":"10.1089\/pho.2013.3590","type":"journal-article","created":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T13:21:18Z","timestamp":1386940878000},"page":"54-57","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":57,"title":["Cutaneous Sporotrichosis Treated with Photodynamic Therapy: An\n                    <i>in Vitro<\/i>\n                    and\n                    <i>in Vivo<\/i>\n                    Study"],"prefix":"10.1177","volume":"32","author":[{"given":"Yolanda","family":"Gilaberte","sequence":"first","affiliation":[{"name":"Hospital San Jorge","place":["Spain"]},{"name":"Institute of Health Sciences of Aragon","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Aspiroz","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences of Aragon","place":["Spain"]},{"name":"Hospital Royo Villanova","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Carmen","family":"Alejandre","sequence":"additional","affiliation":[{"name":"Tonw Hall Institute of Public Health","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Andres-Ciriano","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences of Aragon","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blanca","family":"Fortu\u00f1o","sequence":"additional","affiliation":[{"name":"Institute of Health Sciences of Aragon","place":["Spain"]},{"name":"Hospital Royo Villanova","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Charlez","sequence":"additional","affiliation":[{"name":"Hospital Royo Villanova","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jose","family":"Revillo","sequence":"additional","affiliation":[{"name":"University Hospital Miguel Servet","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Hamblin","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital"},{"name":"Harvard Medical School"},{"name":"Harvard-MIT Division of Health Sciences and Technology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Rezusta","sequence":"additional","affiliation":[{"name":"University Hospital Miguel Servet","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1086\/313751","article-title":"Practice guidelines for the management of patients with sporotrichosis. For the Mycoses Study Group. Infectious Diseases Society of America","volume":"30","author":"Kauffman C.A.","year":"2000","unstructured":"Kauffman C.A., , Hajjeh R., , and Chapman S.W. (2000). Practice guidelines for the management of patients with sporotrichosis. For the Mycoses Study Group. Infectious Diseases Society of America. Clin. Infect. Dis., 30, 684\u2013687.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1992.tb04222.x"},{"key":"e_1_3_3_4_2","first-page":"120","article-title":"Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform","volume":"3","author":"Dai T.","year":"2012","unstructured":"Dai T., , Fuchs B.B., , Coleman J.J., , Prates R.A., , Astrakas C., , St. Denis T.G., et al. (2012). Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front. Microbiol., 3, 120.","journal-title":"Front. Microbiol."},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s11046-011-9434-6","article-title":"Photodynamic antifungal therapy against chromoblastomycosis","volume":"172","author":"Lyon J.P.","year":"2011","unstructured":"Lyon J.P., , Pedroso e Silva Azevedo Cde M., , Moreira L.M., , de Lima C.J., , and de Resende M.A. (2011). Photodynamic antifungal therapy against chromoblastomycosis. Mycopathologia, 172, 293\u2013297.","journal-title":"Mycopathologia"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s11046-010-9325-2","article-title":"Photodynamic therapy in the treatment of superficial mycoses: an evidence-based evaluation","volume":"170","author":"Qiao J.","year":"2010","unstructured":"Qiao J., , Li R., , Ding Y., , and Fang H. (2010). Photodynamic therapy in the treatment of superficial mycoses: an evidence-based evaluation. Mycopathologia, 170, 339\u2013343.","journal-title":"Mycopathologia"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2012.3225"},{"key":"e_1_3_3_8_2","first-page":"626","article-title":"Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication","volume":"29","author":"Aspiroz C.","year":"2011","unstructured":"Aspiroz C., , Gilaberte Y., , Paz\u2013Cristobal P., , and Rezusta A. (2011). Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication. Enferm. Infecc. Microbiol. Clin., 29, 626\u2013628.","journal-title":"Enferm. Infecc. Microbiol. Clin."},{"key":"e_1_3_3_9_2","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.jaad.2010.06.008","article-title":"Treatment of refractory fingernail onychomycosis caused by nondermatophyte molds with methylaminolevulinate photodynamic therapy","volume":"65","author":"Gilaberte Y.","year":"2011","unstructured":"Gilaberte Y., , Aspiroz C., , Martes M.P., , Alcalde V., , Espinel\u2013Ingroff A., , and Rezusta A. (2011). Treatment of refractory fingernail onychomycosis caused by nondermatophyte molds with methylaminolevulinate photodynamic therapy. J. Am. Acad. Dermatol., 65, 669\u2013671.","journal-title":"J. Am. Acad. Dermatol."},{"key":"e_1_3_3_10_2","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1089\/pho.2006.24.528","article-title":"New photodynamic therapy protocol to treat AIDS-related Kaposi's sarcoma","volume":"24","author":"Tardivo J.P.","year":"2006","unstructured":"Tardivo J.P., , Del Giglio A., , Paschoal L.H., , and Baptista M.S. (2006). New photodynamic therapy protocol to treat AIDS-related Kaposi's sarcoma. Photomed. Laser Surg., 24, 528\u2013531.","journal-title":"Photomed. Laser Surg."},{"key":"e_1_3_3_11_2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1600-0781.2004.00095.x","article-title":"Photodynamic therapy of interdigital mycoses of the feet with topical application of 5-aminolevulinic acid","volume":"20","author":"Calzavara\u2013Pinton P.G.","year":"2004","unstructured":"Calzavara\u2013Pinton P.G., , Venturini M., , Capezzera R., , Sala R., , and Zane C. (2004). Photodynamic therapy of interdigital mycoses of the feet with topical application of 5-aminolevulinic acid. Photodermatol. Photoimmunol. Photomed., 20, 144\u2013147.","journal-title":"Photodermatol. Photoimmunol. Photomed."},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","first-page":"8623","DOI":"10.1128\/AEM.02414-12","article-title":"Biosynthesis and functions of a melanoid pigment produced by species of the sporothrix complex in the presence of L-tyrosine","volume":"78","author":"Almeida\u2013Paes R.","year":"2012","unstructured":"Almeida\u2013Paes R., , Frases S., , Araujo Gde S., , de Oliveira M.M., , Gerfen G.J., , Nosanchuk J.D., et al. (2012). Biosynthesis and functions of a melanoid pigment produced by species of the sporothrix complex in the presence of L-tyrosine. Appl. Environ. Microbiol., 78, 8623\u20138630.","journal-title":"Appl. Environ. Microbiol."},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1439-0507.2012.02226.x","article-title":"In vitro photodynamic therapy against Foncecaea pedrosoi and Cladophialophora carrionii","volume":"56","author":"Lyon J.P.","year":"2013","unstructured":"Lyon J.P., , Moreira L.M., , de Carvalho V.S., , dos Santos F.V., , de Lima C.J., , and de Resende M.A. (2013). In vitro photodynamic therapy against Foncecaea pedrosoi and Cladophialophora carrionii. Mycoses, 56, 157\u2013161.","journal-title":"Mycoses"},{"key":"e_1_3_3_14_2","doi-asserted-by":"crossref","first-page":"649","DOI":"10.3109\/13693786.2012.655258","article-title":"A refractory case of chromoblastomycosis due to Fonsecaea monophora with improvement by photodynamic therapy","volume":"50","author":"Yang Y.","year":"2012","unstructured":"Yang Y., , Hu Y., , Zhang J., , Li X., , Lu C., , Liang Y., et al. (2012). A refractory case of chromoblastomycosis due to Fonsecaea monophora with improvement by photodynamic therapy. Med. Mycol., 50, 649\u2013653.","journal-title":"Med. Mycol."},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04389"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1L051"},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1128\/JCM.00255-11","article-title":"Antifungal susceptibilities of Sporothrix albicans, S. brasiliensis, and S. luriei of the S. schenckii complex identified in Brazil","volume":"49","author":"Oliveira D.C.","year":"2011","unstructured":"Oliveira D.C., , Lopes P.G., , Spader T.B., , Mahl C.D., , Tronco\u2013Alves G.R., , Lara V.M., et al. (2011). Antifungal susceptibilities of Sporothrix albicans, S. brasiliensis, and S. luriei of the S. schenckii complex identified in Brazil. J. Clin. Microbiol., 49, 3047\u20133049.","journal-title":"J. Clin. Microbiol."}],"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/pho.2013.3590","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2013.3590","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2013.3590","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:37:15Z","timestamp":1777678635000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/full\/10.1089\/pho.2013.3590"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1089\/pho.2013.3590"],"URL":"https:\/\/doi.org\/10.1089\/pho.2013.3590","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}