{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:18:21Z","timestamp":1777929501499,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    The aim of this study was to propose an autofluorescence (AF)-guided surgical approach performed with Er:YAG laser and Nd:YAG low-level laser therapy (LLLT).\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background data:<\/jats:italic>\n                    <\/jats:bold>\n                    Medication-related osteonecrosis of the jaw (MRONJ) therapy remains an unresolved problem. The proposed conservative and surgical treatment regimens are associated with contradictory success rates. However, the increased experience with MRONJ management suggests that surgical therapy can halt disease progression, and can allow a histology-based diagnosis of osteonecrosis. Surgical approach with Er:YAG laser is associated with significantly better results compared with medical treatment and traditional surgical approaches. One of the difficulties encountered during surgical removal of a MRONJ is the precise individuation of necrotic bone margins.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Patient and methods:<\/jats:italic>\n                    <\/jats:bold>\n                    A case of Stage III maxillary osteonecrosis treated with a new surgical approach is presented.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    After 7 months of follow-up, complete mucosal healing was evident, and the patient was free of symptoms. Such a technique allowed a highly accurate and minimally invasive approach through the selective ablation of the non-\/hypofluorescent areas.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    Taking into account the advantages of laser therapy and the possible effectiveness of AF in highlighting surgical margins, this approach would probably achieve excellent outcomes.\n                  <\/jats:p>","DOI":"10.1089\/pho.2015.3927","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T14:52:41Z","timestamp":1438267961000},"page":"437-442","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Medication-Related Osteonecrosis of the Jaw: An Autofluorescence-Guided Surgical Approach Performed with Er:YAG Laser"],"prefix":"10.1177","volume":"33","author":[{"given":"Paolo","family":"Vescovi","sequence":"first","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Giovannacci","sequence":"additional","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Otto","sequence":"additional","affiliation":[{"name":"Ludwig-Maximilians Universit\u00e4t M\u00fcnchen","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maddalena","family":"Manfredi","sequence":"additional","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Merigo","sequence":"additional","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Fornaini","sequence":"additional","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Nammour","sequence":"additional","affiliation":[{"name":"University of Liege","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Meleti","sequence":"additional","affiliation":[{"name":"University of Parma","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,8]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"115","article-title":"Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic","volume":"61","author":"Marx RE","year":"2003","unstructured":"Marx RE. 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