{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T21:54:55Z","timestamp":1781560495628,"version":"3.54.5"},"reference-count":8,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2016,8,25]],"date-time":"2016-08-25T00:00:00Z","timestamp":1472083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    This retrospective case series was designed to compare the long-term safety and efficacy of bipolar fractional radiofrequency (FRF) therapy as a treatment for atrophic acne scars (ASs) and acne vulgaris.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background data:<\/jats:italic>\n                    <\/jats:bold>\n                    Few clinical and histological studies have examined the long-term utility of bipolar FRF therapy as a treatment for ASs and acne in people with darker skin.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Materials and methods:<\/jats:italic>\n                    <\/jats:bold>\n                    Eight Japanese patients with ASs and mild-to-severe acne on both cheeks were treated with a bipolar FRF system (eMatrix; Syneron). Five treatment sessions with the same settings (coverage rate: 10%; peak energy: 62\u2009mJ\/pin; two passes) were carried out at 1-month intervals, and the patients were followed up for at least 1 year after the final treatment. Assessments of ASs and acne severity were performed and samples were removed for histological examination.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    We demonstrated that mild ASs responded better than moderate and severe ASs, and at least 50% improvement in scar severity was seen in 50% of patients after the final treatment. Six patients remained disease free at 1.5 years without the use of any additional therapies. The biopsy specimens showed a marked improvement characterized by a decrease in dermal pilosebaceous units and perivascular inflammatory cell infiltrates with an increase in elastin content and collagen deposition in the upper dermis.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    Bipolar FRF treatment showed long-term effectiveness against mild ASs and acne in Asian patients and had minimal side effects.\n                  <\/jats:p>","DOI":"10.1089\/pho.2016.4116","type":"journal-article","created":{"date-parts":[[2016,8,26]],"date-time":"2016-08-26T12:41:05Z","timestamp":1472215265000},"page":"657-660","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Long-Term Clinical and Histological Effects of a Bipolar Fractional Radiofrequency System in the Treatment of Facial Atrophic Acne Scars and Acne Vulgaris in Japanese Patients: A Series of Eight Cases"],"prefix":"10.1177","volume":"34","author":[{"given":"Chikako","family":"Kaminaka","sequence":"first","affiliation":[{"name":"Wakayama Medical University","place":["Japan"]},{"name":"Wakayama Medical University","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fukumi","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Wakayama Medical University","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Wakayama Medical University","place":["Japan"]},{"name":"Wakayama Medical University","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,8,25]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.01.019"},{"key":"e_1_3_4_3_2","first-page":"9","article-title":"Sublative rejuvenation: experience with a new fractional radiofrequency system for skin rejuvenation and repair","volume":"8","author":"Brightman L","year":"2009","unstructured":"Brightman L, , Goldman MP, , Taub AF. Sublative rejuvenation: experience with a new fractional radiofrequency system for skin rejuvenation and repair. J Drugs Dermatol, 2009; 8:9\u201313.","journal-title":"J Drugs Dermatol"},{"key":"e_1_3_4_4_2","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1097\/01.DSS.0000452625.01889.c3","article-title":"Objective evaluation of the clinical efficacy of fractional radiofrequency treatment for acne scars and enlarged pores in Asian skin","volume":"40","author":"Kim JE","year":"2014","unstructured":"Kim JE, , Lee HW, , Kim JK, et al. Objective evaluation of the clinical efficacy of fractional radiofrequency treatment for acne scars and enlarged pores in Asian skin. Dermatol Surg, 2014; 40:988\u2013995.","journal-title":"Dermatol Surg"},{"key":"e_1_3_4_5_2","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/j.1365-2133.2012.10870.x","article-title":"Fractional laser resurfacing for acne scars: review","volume":"166","author":"Ong MWS","year":"2012","unstructured":"Ong MWS, , Bashir SJ. Fractional laser resurfacing for acne scars: review. Br J Dermatol, 2012; 166:1160\u20131169.","journal-title":"Br J Dermatol"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2007.05.005"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2014.3733"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12483"},{"key":"e_1_3_4_9_2","first-page":"1","article-title":"A Histological study on the treatment of acne scars with fractional radiofrequency: preliminary findings","volume":"5","author":"Omi T","year":"2014","unstructured":"Omi T, , Sato S, , Kaminaka C, et al. A Histological study on the treatment of acne scars with fractional radiofrequency: preliminary findings. J Clin Exp Dermatol Res, 2014; 5:1\u20135.","journal-title":"J Clin Exp Dermatol Res"}],"container-title":["Photomedicine and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/pho.2016.4116","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2016.4116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/pho.2016.4116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T21:35:50Z","timestamp":1781559350000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/pho.2016.4116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,25]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1089\/pho.2016.4116"],"URL":"https:\/\/doi.org\/10.1089\/pho.2016.4116","relation":{},"ISSN":["1549-5418","1557-8550"],"issn-type":[{"value":"1549-5418","type":"print"},{"value":"1557-8550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,25]]}}}