{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:20:04Z","timestamp":1790648404538,"version":"4.1.0"},"reference-count":35,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    In this split-mouth clinical trial, we evaluated the clinical benefits of low-level laser therapy (LLLT) as an adjunct to nonsurgical periodontal treatment in patients with type 2 diabetes mellitus (DM).\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background data:<\/jats:italic>\n                    <\/jats:bold>\n                    The impaired wound healing seen in diabetic patients may affect the results of periodontal treatment and may require an additional approach.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Materials and methods:<\/jats:italic>\n                    <\/jats:bold>\n                    In total, 22 chronic periodontitis patients with type 2 DM were included. Applying a split-mouth design, two quadrants were treated with only scaling and root planing (SRP) as the control and those in the other two were treated with SRP + LLLT as the test sites in each patient. An 808\u2009nm GaAlAs diode laser was performed in the test sites at the energy density of 4.46\u2009J\/cm\n                    <jats:sup>2<\/jats:sup>\n                    on days 1, 2, and 7 after SRP. Plaque index (PI), probing depth (PD), bleeding on probing (BOP), and clinical attachment level were measured at baseline and again at 1 and 3 months after treatment. Deep periodontal pockets (PD \u22654\u2009mm) were evaluated separately.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    Test sites showed significant improvement in PI and BOP in deep pockets at the 1-month follow-up period (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u20090.001 and &lt;0.001, respectively), whereas no difference was found between the control and the test sites in other periodontal parameters.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    LLLT during periodontal treatment offered minimal short-term additional benefit in deep pocket healing in patients with type 2 DM.\n                  <\/jats:p>","DOI":"10.1089\/pho.2016.4117","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T17:05:55Z","timestamp":1479402355000},"page":"111-115","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":32,"title":["Role of Low-Level Laser Therapy as an Adjunct to Initial Periodontal Treatment in Type 2 Diabetic Patients: A Split-Mouth, Randomized, Controlled Clinical Trial"],"prefix":"10.1177","volume":"35","author":[{"given":"Oya","family":"Demirturk-Gocgun","sequence":"first","affiliation":[{"name":"Istanbul University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulku","family":"Baser","sequence":"additional","affiliation":[{"name":"Istanbul University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokce","family":"Aykol-Sahin","sequence":"additional","affiliation":[{"name":"Okan University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevin","family":"Dinccag","sequence":"additional","affiliation":[{"name":"Istanbul University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halim","family":"Issever","sequence":"additional","affiliation":[{"name":"Istanbul University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Funda","family":"Yalcin","sequence":"additional","affiliation":[{"name":"Istanbul University","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,2]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2006.00193.x"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2008.01442.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2005.05.006"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1998.69.1.76"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2002.300304.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900050105"},{"key":"e_1_3_3_8_2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/lsm.10107","article-title":"Effect of low-power laser irradiation on cell growth and pro-collagen synthesis of cultured fibroblasts","volume":"31","author":"Pereira AN","year":"2002","unstructured":"Pereira AN, , Eduardo Cde P, , Matson E, , Marques MM. 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