{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T09:16:54Z","timestamp":1782897414533,"version":"3.54.5"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photomedicine and Laser Surgery"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Objective:<\/jats:italic>\n                    <\/jats:bold>\n                    To compare the safety and efficacy of pulsed dye laser (PDL) at different intervals for the treatment of East Asians with Port-Wine Stain (PWS).\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Background:<\/jats:italic>\n                    <\/jats:bold>\n                    The population of East Asians around the world is about 1.6 billion, and they are considered to have more melanin in their skin compared with Caucasians. Nevertheless, no studies about the optimal treatment intervals for East Asians with PWS have been carried out.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                    <\/jats:bold>\n                    We prospectively investigated 39 East Asian patients with untreated PWS. Half of the PWS lesion was randomly allocated to be treated at 3 weeks and the other half at 6 weeks. Both halves of the PWS were treated three times in total. The efficacy outcome 2 months post final treatment was evaluated by visual and chromameter evaluation.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Results:<\/jats:italic>\n                    <\/jats:bold>\n                    The average blanching rate was 40.27% and 44.17% for PDL treatments at the 3- and 6-week interval sites, respectively (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&gt;\u20090.05). No patient developed scarring or permanent pigmentation change.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Limitations:<\/jats:italic>\n                    <\/jats:bold>\n                    There was no age criteria involved in the enrollment of patients in this study. Additionally, there is no comparison with long-term treatments at different intervals.\n                    <jats:bold>\n                      <jats:italic toggle=\"yes\">Conclusions:<\/jats:italic>\n                    <\/jats:bold>\n                    PDL treatment at 3-week interval proved to be safe for East Asians with PWS. This can reduce the total duration of the course of treatments and had no increase in side effects compared with the standard interval treatments.\n                  <\/jats:p>","DOI":"10.1089\/pho.2017.4315","type":"journal-article","created":{"date-parts":[[2017,10,10]],"date-time":"2017-10-10T10:22:09Z","timestamp":1507630929000},"page":"37-43","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Shorter Treatment Intervals of East Asians with Port-Wine Stain with Pulsed Dye Laser Are Safe and Effective\u2014A Prospective Side-by-Side Comparison"],"prefix":"10.1177","volume":"36","author":[{"given":"Wenxin","family":"Yu","sequence":"first","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiafang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Changc","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunbo","family":"Jin","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Yang","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyou","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chang","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Ma","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxi","family":"Lin","sequence":"additional","affiliation":[{"name":"Shanghai Jiaotong University","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,1]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.58.2.218"},{"key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.jaad.2012.05.027","article-title":"Hypertrophy in port-wine stains: prevalence and patient characteristics in a large patient cohort","volume":"67","author":"Van Drooge AM","year":"2012","unstructured":"Van Drooge AM, , Beek JF, , van der Veen JP, , van der Horst CM, , Wolkerstorfer A. Hypertrophy in port-wine stains: prevalence and patient characteristics in a large patient cohort. J Am Acad Dermatol, 2012; 67:1214\u20131219.","journal-title":"J Am Acad Dermatol"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb01800.x"},{"key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2133.2004.06163.x","article-title":"Recent advances in laser treatment of port-wine stains","volume":"151","author":"Lanigan SW","year":"2014","unstructured":"Lanigan SW, , Taibjee SM. Recent advances in laser treatment of port-wine stains. Br J Dermatol, 2014; 151:527\u2013533.","journal-title":"Br J Dermatol"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1996)19:2<224::AID-LSM15>3.0.CO;2-6"},{"key":"e_1_3_3_7_2","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/j.1365-2133.2005.07113.x","article-title":"The treatment of port-wine stains with the pulsed-dye laser at 2-week and 6-week intervals: a comparative study","volume":"154","author":"Tomson N","year":"2006","unstructured":"Tomson N, , Lim SP, , Abdullah A, , Lanigan SW. The treatment of port-wine stains with the pulsed-dye laser at 2-week and 6-week intervals: a comparative study. 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