{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:56:26Z","timestamp":1790808986804,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2024,8]]},"abstract":"\n Aim:<\/jats:title>\n \n The study aims to assess the efficacy of rose bengal (RB)-mediated antimicrobial photodynamic therapy (a-PDT) as an adjunct to scaling and root planing in the management of chronic periodontitis patients in terms of clinical parameters like gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), and microbiological parameters like total microbial count, total red complex organism count,\n Porphyromonas gingivalis<\/jats:italic>\n count,\n Treponema denticola<\/jats:italic>\n count, and\n Tannerella forsythia<\/jats:italic>\n count.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n In this randomized controlled clinical trial, a total of 30 patients were recruited who met the inclusion criteria. The participants were randomly allocated into group A with scaling and root planning (SRP) alone and group B with SRP + a-PDT. The clinical and microbiological parameters were measured at baseline and at 3-month follow-up. Intergroup and intragroup comparisons were performed using independent\n t<\/jats:italic>\n test and paired\n t<\/jats:italic>\n test, respectively. Value of\n p<\/jats:italic>\n < 0.05 was considered as statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n At 3-month follow-up, group B treated with SRP + a-PDT showed statistically significant reduction in GI (0.58 \u00b1 0.20) and PPD (1.81 \u00b1 0.32 mm), gain in CAL (0.73 \u00b1 0.04 mm), and reduction in total microbial count [2.80 \u00b1 0.08 \u00d7 10\n 4<\/jats:sup>\n colony forming unit (CFU)], total red complex count (0.29 \u00b1 0.14 \u00d7 10\n 2<\/jats:sup>\n CFU),\n P. gingivalis<\/jats:italic>\n count (0.43 \u00b1 0.13 \u00d7 10\n 2<\/jats:sup>\n CFU),\n T. denticola<\/jats:italic>\n count (0.61 \u00b1 0.04 \u00d7 10\n 2<\/jats:sup>\n CFU), and\n T. forsythia<\/jats:italic>\n count (0.59 \u00b1 0.04 \u00d7 10\n 2<\/jats:sup>\n CFU) as compared with group A (\n p<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n RB-mediated a-PDT as an adjunct to SRP was significantly more effective in improving GI, PPD, and CAL and in reducing microbial count as compared with SRP alone in the management of chronic periodontitis.<\/jats:p>\n <\/jats:sec>","DOI":"10.1089\/pho.2024.0037","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T05:21:50Z","timestamp":1721020910000},"page":"561-567","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of Rose Bengal-Mediated Antimicrobial Photodynamic Therapy as an Adjunct to Scaling and Root Planing on Clinical and Microbiological Parameters in the Management of Chronic Periodontitis: A Single-Blinded, Randomized Controlled Clinical Trial"],"prefix":"10.1177","volume":"42","author":[{"given":"Nivedha","family":"Nedumaran","sequence":"first","affiliation":[{"name":"Department of Periodontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvina","family":"Rajasekar","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, 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