{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:10:24Z","timestamp":1787008224772,"version":"build-2736575974"},"reference-count":42,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine optimal settings for use of diode lasers to treat vascular malformations in the head and neck.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Diode lasers are generally accepted as effective tools to treat vascular malformations in the head and neck, yet there are no standardized treatment protocols for this treatment approach. Settings for these lasers, in addition to laser type and size and lesion depth are important variables for designing appropriate treatments for vascular malformations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>Vascular venous malformations (VeMs) were classified into five groups according to high-definition ultrasound measurements of superficial dimensions (&lt;1, 1\u20133, and &gt;3\u2009cm) and lesion extension depth (\u22645, and &gt;5\u2009mm). Using a 800\u2009\u00b1\u200910\u2009nm diode laser for surgical procedures, we treated lesions by two different approaches: trans-mucous\/cutaneous photocoagulation (8 and 12\u2009W pulsed wave for cutaneous and mucosal lesions, respectively) and intralesional photocoagulation using a laser set to 13\u2009W in the pulsed wave modality to treat both cutaneous and mucosal lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We treated 158 vascular VeMs. According to preoperative staging, there were 52 lesions in Group A (superficial dimension &lt;1\u2009cm), 28 in Group B\n                      <jats:sub>1<\/jats:sub>\n                      (superficial dimension from 1 to 3\u2009cm, extension depth \u22645\u2009mm), 16 in Group B\n                      <jats:sub>2<\/jats:sub>\n                      (superficial dimension from 1 to 3\u2009cm, extension depth &gt;5\u2009mm), 42 in Group C\n                      <jats:sub>1<\/jats:sub>\n                      (superficial dimension &gt;3\u2009cm, extension depth \u22645\u2009mm), and 12 in Group C\n                      <jats:sub>2<\/jats:sub>\n                      (superficial dimension &gt;3\u2009cm, extension depth &gt;5\u2009mm). All Group A lesions showed complete healing after a single laser treatment, whereas 7%, 10%, 12%, and 16% of lesions classified in Groups B\n                      <jats:sub>1<\/jats:sub>\n                      , B\n                      <jats:sub>2<\/jats:sub>\n                      , C\n                      <jats:sub>1<\/jats:sub>\n                      , and C\n                      <jats:sub>2<\/jats:sub>\n                      , respectively, required further treatments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The laser settings defined in this study were associated with a reduced number of laser applications needed for effective treatment of vascular VeMs. Moreover, the cooling of irradiated tissues, together with prolonged application of a topical regenerative gel, provided good treatment acceptability, reduced the number of postoperative complications, and promoted faster healing of covering tissues.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2019.4635","type":"journal-article","created":{"date-parts":[[2019,9,27]],"date-time":"2019-09-27T11:10:13Z","timestamp":1569582613000},"page":"722-728","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Diode Laser Photocoagulation of Intraoral and Perioral Venous Malformations After Tridimensional Staging by High Definition Ultrasonography"],"prefix":"10.1177","volume":"37","author":[{"given":"Luisa","family":"Limongelli","sequence":"first","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Tempesta","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio","family":"De Caro","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Maiorano","sequence":"additional","affiliation":[{"name":"Department of Emergency and Organ Transplantation, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Angelelli","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saverio","family":"Capodiferro","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Favia","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Medicine, Universit\u00e0 degli Studi di Bari Aldo Moro, Bari, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,12]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198203000-00002"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198207000-00041"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(83)80043-8"},{"key":"e_1_3_3_5_2","volume-title":"Soft Tissue Tumors","author":"Enzinger FM","year":"2001","unstructured":"Enzinger FM, , Weiss SW. 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