{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:20:21Z","timestamp":1777929621458,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Rectovaginal fistulas (RVFs) are defined as any connection between the anorectum and the vagina. They can have several causes, being Crohn's disease, the second leading cause of RVFs, responsible for \u223c10% of the RVFs. Despite the advances in surgical and clinical treatment, there is no consensus regarding the best line of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      To report another therapeutic option, we describe the case of a patient with Crohn's disease and RVF refractory to anti-tumor necrosis factor (TNF) therapy, submitted to intravaginal CO\n                      <jats:sub>2<\/jats:sub>\n                      fractional laser treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>Three laser sessions with monthly interval and analysis by clinical examination, sexual evaluation questionnaire, and magnetic resonance of the pelvis were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We obtained an important improvement of the symptoms and of the dimension of the fistulous path.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>We believe this method to be a complementary, promising, and safe therapeutic alternative for the management of vaginal fistula. Future studies using this therapeutic strategy are needed to confirm the efficacy of this method in this clinical setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2019.4643","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T10:45:36Z","timestamp":1560854736000},"page":"451-454","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Treatment for Rectovaginal Fistula in Crohn's Disease Using Fractionate CO\n                    <sub>2<\/sub>\n                    Vaginal Laser with Anti-TNF Therapy"],"prefix":"10.1177","volume":"37","author":[{"given":"Denise Gasparetti","family":"Drumond","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Universidade Federal de Juiz de Fora Faculdade de Medicina, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falio Maria Fonseca","family":"Chebli","sequence":"additional","affiliation":[{"name":"Department of Medical Clinic, Universidade Federal de Juiz de Fora Faculdade de Medicina, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neila Maria de G\u00f3is","family":"Speck","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Federal University of S\u00e3o Paulo, Sao Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana Andrade","family":"Chebli","sequence":"additional","affiliation":[{"name":"Department of Medical Clinic, Universidade Federal de Juiz de Fora Faculdade de Medicina, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Duque","family":"Pannain","sequence":"additional","affiliation":[{"name":"Universidade Federal de Juiz de Fora Faculdade de Medicina, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel Drumond","family":"Esperan\u00e7a","sequence":"additional","affiliation":[{"name":"Faculdade de Ciencias Medicas e da Saude de Juiz de Fora, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila de Moraes Sarmento","family":"Cond\u00e9","sequence":"additional","affiliation":[{"name":"Ultraimagem, Juiz de Fora, Minas Gerais, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,7,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2009.09.003"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-011-1917-5"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.22836"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00414-8"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000980"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000607"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3109\/13697137.2014.899347"},{"key":"e_1_3_2_9_2","first-page":"89","article-title":"Female sexual quotient: a Brazilian number to evaluate a woman's sexual activity","volume":"14","author":"Abdo CHN","year":"2009","unstructured":"Abdo CHN. Female sexual quotient: a Brazilian number to evaluate a woman's sexual activity. Diagn Tratamento, 2009; 14:89\u201391.","journal-title":"Diagn Tratamento"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2017.1296355"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13083"},{"key":"e_1_3_2_12_2","first-page":"1","article-title":"Fractional CO2 laser: from Skin rejuvenation to vulvo-vaginal reshaping","volume":"20","author":"Filippini M","year":"2017","unstructured":"Filippini M, , Del Duca E, , Negosanti F, et al. Fractional CO2 laser: from Skin rejuvenation to vulvo-vaginal reshaping. Photomed Laser Surg, 2017; 20:1\u20135.","journal-title":"Photomed Laser Surg"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-016-4118-6"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000000700"}],"container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1089\/photob.2019.4643","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/photob.2019.4643","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1089\/photob.2019.4643","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:46:11Z","timestamp":1777679171000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1089\/photob.2019.4643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1089\/photob.2019.4643"],"URL":"https:\/\/doi.org\/10.1089\/photob.2019.4643","relation":{},"ISSN":["2578-5478","2578-5478"],"issn-type":[{"value":"2578-5478","type":"print"},{"value":"2578-5478","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}