{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T04:28:34Z","timestamp":1782534514236,"version":"3.54.5"},"reference-count":44,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To conduct a preliminary assessment of the intense pulsed light (IPL) treatment on the upper eyelid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>IPL therapy is an effective therapy for meibomian gland dysfunction (MGD). The normal treatment region includes the skin below the lower eyelids and both temporal parts, but not the upper eyelid.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty patients with mid-to-severe dry eye disease caused by MGD were selected and randomly divided into two groups. Fifteen controls in group A received normal IPL treatment. Fifteen patients in Group B underwent additional IPL treatment on the upper eyelid. The change in noninvasive tear breakup time (BUT), Ocular Surface Disease Index (OSDI) questionnaire, patient satisfaction, and adverse events were measured and recorded at each visit, before each treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The dry eye symptoms of the patients in both groups improved. The patients in group B had better recovery than those in group A: BUT (right eye: 11.6\u2009\u00b1\u20093.67\u2009sec vs. 7.73\u2009\u00b1\u20091.99\u2009sec; left eye: 12.73\u2009\u00b1\u20094.19\u2009sec vs. 7.73\u2009\u00b1\u20091.40\u2009sec), OSDI (8.87\u2009\u00b1\u20094.31 vs. 14.93\u2009\u00b1\u20093.47); patient satisfaction in group B remained good, but decreased in group A with prolonged treatment duration. No serious skin and eye complications were found in any patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This study showed the patients who received IPL treatment on the upper eyelid experienced improved symptoms of MGD. A further long-term study should be conducted to increase our understanding of the effect of expanded IPL treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2019.4689","type":"journal-article","created":{"date-parts":[[2020,4,17]],"date-time":"2020-04-17T11:11:42Z","timestamp":1587121902000},"page":"249-254","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Preliminary Assessment of Intense Pulsed Light Treatment on the Upper Eyelids for Meibomian Gland Dysfunction"],"prefix":"10.1177","volume":"38","author":[{"given":"Dan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou, China."},{"name":"Department of Plastic Surgery, Southern Medical University, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Bin","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Zhi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Joint Shantou International Eye Center of Shantou University and Chinese University of Hong Kong, Shantou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, Southern Medical University, Guangzhou, China."},{"name":"Department of Burn and Plastic Surgery, General Hospital of Southern Theater Command, PLA, Guangzhou, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,4,16]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(93)31643-X"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-5359-5_45"},{"key":"e_1_3_5_4_2","first-page":"225","article-title":"Changes in human meibum with meibomian gland dysfunction [in Chinese]","volume":"51","author":"Hu X","year":"2015","unstructured":"Hu X, , Lyu H, , Jiang X, , Li X. 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