{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:21:06Z","timestamp":1777929666198,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Rectovaginal fistulas (RVFs) are abnormal tracts that connect the lower gastrointestinal tract with the vagina. They can result from obstetric trauma, infection, local surgeries, cancer, radiation damage, and Crohn's disease. Despite the advances in surgical and clinical treatment, there is no consensus regarding the best line of treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>\n                      To report five cases of patients with RVF submitted to intravaginal CO\n                      <jats:sub>2<\/jats:sub>\n                      fractional laser treatment, as a complementary and additional therapeutic option in this scenery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>Five laser sessions with monthly intervals followed by complete evaluation through clinical examination and magnetic resonance imaging of the pelvis were performed for all patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Three patients had complete resolution of symptoms after the end of planned vaginal laser sessions, whereas two patients reported significant improvement in symptoms. Four patients who had stopped having sex due to their condition admitted to resuming regular sexual activity. In addition, all five patients had closure of the fistulous track confirmed by pelvic MRI. No adverse events from vaginal laser therapy were reported by any of the patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>We believe this method to be a complementary, promising, and safe therapeutic alternative for the management of RVF. It may potentially enable return to regular sexual activity. Future studies using this therapeutic strategy are needed to confirm the efficacy and safety of this method in this clinical setting.<\/jats:p>\n                    <jats:p>Clinical trial registration no.: CAAE 93673618.4.0000.5133.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2020.4992","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T10:21:40Z","timestamp":1632219700000},"page":"622-629","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of Rectovaginal Fistula Using Fractionate CO\n                    <sub>2<\/sub>\n                    Vaginal Laser: A Case Series"],"prefix":"10.1177","volume":"39","author":[{"given":"Denise Gasparetti","family":"Drumond","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neila Maria","family":"de G\u00f3is Speck","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Federal University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falio Maria Fonseca","family":"Chebli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"de Moraes Sarmento Cond\u00e9","sequence":"additional","affiliation":[{"name":"Radiologist."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liliana Andrade","family":"Chebli","sequence":"additional","affiliation":[{"name":"Department of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Duque","family":"Pannain","sequence":"additional","affiliation":[{"name":"University Hospital of Federal University of Juiz de Fora, Juiz de Fora, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel Drumond","family":"Esperan\u00e7a","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, Sao Paulo, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,9,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10350-007-9057-7"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6109(02)00055-5"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2009.09.003"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.22836"},{"key":"e_1_3_3_6_2","first-page":"69","article-title":"Rectovaginal fistula: a review of 11 years experience","volume":"69","author":"Shieh CJ","year":"1984","unstructured":"Shieh CJ, , Gennaro AR. 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