{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T09:49:03Z","timestamp":1791539343970,"version":"4.3.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Evaluate the treatment outcome of vitiligo patients receiving a standard regimen of high-dose biweekly fractional 2940\u2009nm erbium:yttrium aluminium garnet (YAG) laser applications as an add-on to various treatment modalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods:<\/jats:title>\n                    <jats:p>The authors extracted the study population's clinical images before treatment and 3rd-month control from their clinical archive and used the medical records. The primary outcome measure was 50% repigmentation at 3rd-month follow-up. Institutional ethical committee approved the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the evaluated 28 patients, 18 were eligible with 31 treatment regions. All patients received at least one topical agent [steroids, calcineurin inhibitors, or 5-fluorouracil (5-FU)] and 11 patients received either targeted ultraviolet B (UVB) or narrow-band UVB. Of the 31 study regions, 88.8% (8\/9) of facial; 77.7% (7\/9) of dorsal hand; 75% (3\/4) of limb; and 25% (2\/8) of finger lesions achieved 50% repigmentation at 3rd-month control. The facial and dorsal hand lesions' treatment responses were higher than finger lesions (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.008 and 0.03, respectively). Upon evaluating adjuvant treatment modalities, all of the treatment regions receiving targeted UVB (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20094) or topical 5-FU (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u20095) achieved the primary endpoint, whereas severe irritation limited the topical use of 5-FU. The most common adverse effects were mild oozing and crusting related to laser treatments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Even with high-energy settings, fractional erbium: YAG laser does not induce the Koebner phenomenon. Although controlled trials are required to make firm conclusions, fractional erbium: YAG laser was an effective and safe adjunctive option for stable vitiligo in a real-life setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2021.0016","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T10:21:40Z","timestamp":1632219700000},"page":"600-606","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Safety and Efficacy of High-Dose Fractional Erbium: Yttrium Aluminium Garnet Laser in Stable Vitiligo"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9431-2125","authenticated-orcid":false,"given":"Aysenur","family":"Botsali","sequence":"first","affiliation":[{"name":"Department of Dermatology, Gulhane Faculty of Medicine, University of Health Sciences, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9087-0258","authenticated-orcid":false,"given":"Ercan","family":"Caliskan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Gulhane Faculty of Medicine, University of Health Sciences, Ankara, Turkey."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,21]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12373"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22227"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12410"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.12553"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2018.1564232"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22260"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12202"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2018.1509048"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10723.x"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22389"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.12747"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2016.2875"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001890"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-016-1982-z"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.23198"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-017-2282-y"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11197.x"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sder.2008.01.002"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S147413"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.03.015"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-017-2154-5"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2017.1260119"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.07.024"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-018-2516-7"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2836"},{"key":"e_1_3_4_27_2","first-page":"308","article-title":"Vitiligo and intralesional steroids","volume":"69","author":"Vasistha LK","year":"1979","unstructured":"Vasistha LK, , Singh G. 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