{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:20:44Z","timestamp":1792023644616,"version":"4.4.0"},"reference-count":57,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Photobiomodulation, Photomedicine, and Laser Surgery"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>This systematic review aimed to evaluate the adhesive bond strength of restorative materials to caries-affected dentin (CAD) treated with antimicrobial photodynamic therapy (aPDT) in comparison with conventional chemical disinfectants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      Three databases, including the Web of Science, Scopus, and PubMed, were searched to address the focused question: \u201cWhat is the effect of aPDT compared to conventional chemical disinfection techniques on the adhesive bond strength of restorative materials to CAD?.\u201d Search keywords included \u201cdentin*\u201d \u201cadhes bond*\u201d \u201ccaries-affected dentin\u201d \u201cphotodynamic \u201cphotochemotherapy\u201d \u201cphotosensitizing agent\u201d \u201cphototherapy\u201d \u201cphotoradiation\u201d \u201claser\u201d \u201clight activated\u201d \u201cphotoactivated.\u201d A fixed-effects model was used in each meta-analysis and the inverse variance was used to calculate the standard mean difference (SMD). For evaluating the statistical heterogeneity, the Cochrane's\n                      <jats:italic toggle=\"yes\">Q<\/jats:italic>\n                      test and the\n                      <jats:italic toggle=\"yes\">\n                        I\n                        <jats:sup>2<\/jats:sup>\n                      <\/jats:italic>\n                      statistics were used. The risk of bias was evaluated based on the Cochrane Collaboration's tool.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Fourteen studies were included in the qualitative as well as quantitative analysis. The results of the meta-analyses exhibited an SMD of 2.38% [95% confidence interval (CI): 2.03\u20132.73;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.00001], indicating a statistically significant difference in the shear bond strength scores between the tested group (samples treated with aPDT) and the control group (i.e., favoring the sound dentin and\/or conventional chemical disinfectants). Contrarily, an SMD of \u22121.46% (95% CI: \u22122.04 to \u22120.88;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.00001) and \u22120.37% (95% CI: \u22120.70 to \u22120.03;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.03) was observed, indicating a statistically significant difference in the microtensile bond strength (\u03bcTBS), as well as microleakage scores between the tested group (favoring the samples treated with aPDT) and the control group (i.e., sound dentin and\/or conventional chemical disinfectants).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Adhesive bond strength of restorative materials to CAD treated with conventional chemical disinfectants showed superior outcomes compared to photodynamic therapy (aPDT).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1089\/photob.2023.0037","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T14:38:12Z","timestamp":1701095892000},"page":"125-139","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Adhesive Bond Strength of Restorative Materials to Caries-Affected Dentin Treated with Antimicrobial Photodynamic Therapy: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"42","author":[{"given":"Yasser F.","family":"AlFawaz","sequence":"first","affiliation":[{"name":"Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"e_1_3_3_2_2","article-title":"Efficacy of chlorhexidine, Er Cr YSGG laser and photodynamic therapy on the adhesive bond integrity of caries affected dentin","volume":"31","author":"Al Deeb L","year":"2020","unstructured":"Al Deeb L, , Bin-Shuwaish MS, , Abrar E, et al. Efficacy of chlorhexidine, Er Cr YSGG laser and photodynamic therapy on the adhesive bond integrity of caries affected dentin. An in-vitro study. Photodiagn Photodyn Ther, 2020; 31:101875.","journal-title":"An in-vitro study. 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