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The results showed their toxicity in a dose-dependent manner. The green synthesis of SnO\n                      <jats:sub>2<\/jats:sub>\n                      :Au NPs was achieved for the first time using an extract of\n                      <jats:italic toggle=\"yes\">T. polium<\/jats:italic>\n                      medicinal plant as a reducing and stabilizing agent. The produced NPs were examined for their application in photodynamic therapy (PDT) for cancer.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Methylene blue and anthracene were used to confirm that the photosensitizer could produce ROS when excited with UVA radiation. The anticancer activity of SnO\n                      <jats:sub>2<\/jats:sub>\n                      :Au was investigated in vitro using the C26 cell line and an MTT assay, showing that PDT with SnO\n                      <jats:sub>2<\/jats:sub>\n                      :Au NPs could inhibit cancer cell proliferation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      The significant afterglow of the SnO\n                      <jats:sub>2<\/jats:sub>\n                      :Au NPs could cause the generation of ROS to continue several minutes after switching off the light source.\n                    <\/jats:p>\n                  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