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Complete cerebral ischemia was produced by cardiac arrest and the animals' temperature was maintained at 37\u00b0C for periods ranging from 0 to 81 hours before electron microscopy preparation. Electron micrographs of cold cerebral ischemia were generated after stabilizing the rat's temperature at 0\u00b0C after cardiac arrest for periods ranging from 0 hours to 6 months. A qualitative examination of the electron micrographs shows structural signatures of energy depletion such as vessel leaking and chromatin clumping after 1 hour at 37\u00b0C and after 24 hours at 0\u00b0C, followed by synapse degradation after 6 hours at 37\u00b0C and 1 week at 0\u00b0C. Evidence of advanced necrosis was observed after 36 hours at 37\u00b0C and 2 months at 0\u00b0C. 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