{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:42:31Z","timestamp":1783114951551,"version":"3.54.6"},"reference-count":32,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Care"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Individuals with COPD may present extra-pulmonary features such as body composition abnormalities. These patients benefit from exercise training, especially in improving their exercise capacity. However, it is unknown whether the magnitude of improvement in exercise capacity is equally proportional in the different body composition phenotypes. We sought to investigate whether individuals with COPD classified in different body composition phenotypes present differences in the magnitude of improvement of exercise capacity after an exercise training program.\n                    <jats:bold>Methods:<\/jats:bold>\n                    Individuals with COPD were assessed before and after a 3-month high intensity exercise training program regarding their body composition (electrical bioimpedance) and functional exercise capacity (6-min walk test [6MWT]). The individuals were classified in four phenotypes of body composition: normal, sarcopenic, obese, and obese-sarcopenic.\n                    <jats:bold>Results:<\/jats:bold>\n                    Fifty-one subjects (26 men, 66 \u00b1 8\u2009years, body mass index 27 \u00b1 6 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    ; FEV\n                    <jats:sub>1<\/jats:sub>\n                    50 [34\u201364] %predicted) were assessed. After the training program there was significant interaction among body composition phenotypes and variation of fat mass\n                    <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                    = .05) and its respective index\n                    <jats:italic toggle=\"yes\">(P<\/jats:italic>\n                    = .05). There was no interaction between improvement in the 6MWT and the body composition phenotypes; however, sarcopenic and obese-sarcopenic individuals improved significantly their 6MWT, both in distance (30 \u00b1 50 m and 46 \u00b1 48 m, respectively) and in %predicted (4 \u00b1 10 and 7 \u00b1 9, respectively), which did not occur in the two other phenotypes.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    There was interaction of body composition phenotype and variation of fat mass after exercise training. However, the presence of sarcopenia (associated or not with obesity) indicated significant and clinically relevant improvements in the 6MWT.\n                  <\/jats:p>","DOI":"10.1089\/respcare.12695","type":"journal-article","created":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T10:05:39Z","timestamp":1744020339000},"page":"1148-1154","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Changes in Exercise Capacity After Physical Training in Individuals With COPD and Different Body Composition Phenotypes"],"prefix":"10.1177","volume":"70","author":[{"given":"Isabella Ortiz","family":"Garcia","sequence":"first","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kouji","family":"Kakazu","sequence":"additional","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Thais Alves","family":"Lopes","sequence":"additional","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina Couto","family":"Furlanetto","sequence":"additional","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pitta","sequence":"additional","affiliation":[{"name":"Ms. Garcia, Mr. Kakazu, Ms. Lopes, Ms. Medeiros, Dr. Furlanetto, and Prof. Pitta are affiliated with Departamento de Fisioterapia, Laborat\u00f3rio de Pesquisa em Fisioterapia Pulmonar (LFIP), Universidade Estadual de Londrina, Londrina, Brasil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,7]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD). 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